Discovery of immune-boosting fibroblasts offers hope for cancer patients
Southampton scientists working to improve survival for cancer patients have identified a key characteristic of the disease that could make treatment more effective.
19 hours ago
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Localized magnetic fields boost chemotherapy uptake in breast cancer treatment, researchers find
Researchers at the National University of Singapore (NUS) have developed a non-invasive method to improve the effectiveness of chemotherapy while reducing its harmful side effects.
22 hours ago
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Decrease seen in in situ breast cancer since 2009
The incidence of in situ breast cancer has decreased since 2009, consistent with decreasing use of mammography in association with the 2009 U.S. Preventive Services Task Force (USPSTF) guideline change, according to a study ...
18 hours ago
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Would cancer warning labels on alcoholic beverages reduce consumption—or be ignored?
Calling alcohol the third-leading preventable cause of cancer, the U.S. surgeon general on Friday recommended that alcoholic beverages come with the same type of warning label currently used on packs of cigarettes.
22 hours ago
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Childhood cancer genome study reveals hidden variants
Researchers at Dana-Farber Cancer Institute collaborated with multiple institutions to pinpoint rare germline structural variants as risk factors for non-blood-related cancers in children, including tumors in various organs. ...
ING5 inhibits aerobic glycolysis of lung cancer cells: Study
Lung cancer, notorious for its high mortality rates, is a leading cause of cancer-related deaths globally, with metastasis being the primary contributor to poor patient outcomes. A critical factor in this devastating disease ...
22 hours ago
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Novel screening tech enhances identification of cancer-targeting T cell receptors
Researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a new screening technology, Aptamer-based T Lymphocyte Activity Screening and ...
Jan 6, 2025
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The elimination of cervical cancer in NZ is within reach—but not without funding and a plan
After committing to a global plan to eliminate cervical cancer, New Zealand is lagging behind Australia and other countries in how it manages this preventable disease.
Jan 5, 2025
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Tonsil cancer: What is it and how to prevent it
Tonsil cancer is a type of head and neck cancer. Head and neck cancers include cancers of the tongue; the back of the tongue, which you can't see when you look in the mirror; the tonsils; or the throat, which includes several ...
Jan 4, 2025
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Scientists unveil surprising human vs. mouse differences in a major cancer immunotherapy target
Since its discovery in the 1990s, programmed cell death protein 1 (PD-1) has been regarded as a leading target in cancer treatments. A checkpoint receptor that often resides on the surface of immune system cells, the PD-1 ...
Jan 3, 2025
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Advanced imaging uncovers hidden metastases in high-risk prostate cancer cases
A study led by researchers at the UCLA Health Jonsson Comprehensive Cancer Center has found that many cases of high-risk nonmetastatic hormone-sensitive prostate cancer may be more advanced than previously thought.
Jan 3, 2025
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Mini-tumors from circulating breast cancer cells offer new treatment insights
Tumor cells circulating in the blood are the germ cells of breast cancer metastases. They are very rare and have not been propagated in the culture dish until now, which made research into therapy resistance difficult.
Jan 3, 2025
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Surprising 'two-faced' cancer gene role supports paradigm shift in predicting disease
A genetic fault long believed to drive the development of esophageal cancer may in fact play a protective role early in the disease, according to new research published in Nature Cancer. This unexpected discovery could help ...
Jan 3, 2025
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FDA approves subcutaneous opdivo qvantig for most solid tumor indications
The U.S. Food and Drug Administration has approved Opdivo Qvantig (nivolumab and hyaluronidase-nvhy) injection for subcutaneous use for most previously approved adult, solid tumor Opdivo (nivolumab) indications.
Jan 3, 2025
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Improving predictions about brain cancer outcomes with the right imaging criteria
A paper published in the Journal of Clinical Oncology, titled "Comparative Analysis of Intracranial Response Assessment Criteria in Patients With Melanoma Brain Metastases Treated With Combination Nivolumab + Ipilimumab in ...
Jan 3, 2025
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New guidelines for managing blood cancers in pregnancy
A new set of guidelines has been developed to assist with the diagnosis and expert management of serious blood cancers in pregnancy.
Jan 3, 2025
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Mitochondrial DNA plays an underappreciated role in leukemia development
Mitochondria are vital to energy production in cells and so play a key role in fueling cancer growth. However, how mitochondrial DNA (mtDNA) contributes to cancer has been unclear.
Jan 2, 2025
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A 'ticking time bomb' for liver cancer: Liver cells' self-defense mechanism against cancer may backfire
Scientists at University of California San Diego School of Medicine have shed new light on the development of liver cancer, the sixth most frequently diagnosed cancer and fourth leading cause of cancer deaths worldwide.
Jan 2, 2025
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Researchers reveal why the lung is a frequent site of cancer metastasis
More than half of cancer patients in whom the cancer spreads beyond the primary site have lung metastases. What makes the lungs such a tempting place for cancer cells?
Jan 2, 2025
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AI-based ultrasound evaluation can improve ovarian cancer diagnoses
A new international study led by researchers at Karolinska Institutet in Sweden shows that AI-based models can outperform human experts at identifying ovarian cancer in ultrasound images. The study is published in Nature ...
Jan 2, 2025
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Discovery of CAR-T 'memory cells' could boost cancer therapy
Researchers at the University of Colorado Anschutz Medical Campus have discovered that some CAR-T cells engineered to fight cancer and other conditions carry the memory of past encounters with bacteria, viruses and other ...
Jan 2, 2025
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Open-access resource simplifies cancer subtype classification for researchers
A multi-institutional team of scientists has developed a free, publicly accessible resource to aid in classification of patient tumor samples based on distinct molecular features identified by The Cancer Genome Atlas (TCGA) ...
Jan 2, 2025
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A new weapon in the battle against cancer: The story of combo prodrug TTFA-Platin
Cancer is a deadly disease taking the lives of thousands of people worldwide, and researchers are constantly looking for better alternatives for treatment. One of the major breakthroughs is combination therapy—a treatment ...