Pancreatic cancer tumor map uncovers notable differences between primary and metastatic disease
Indiana University Melvin and Bren Simon Comprehensive Cancer Center researchers have mapped pancreatic cancer tumor ecosystems using tissue from both the primary tumor, which is where cancer first starts to grow in the body, ...
Oct 4, 2024
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Research points to potential new treatment for aggressive prostate cancer subtype
When researchers at the University of Michigan Rogel Cancer Center first identified a new subtype of aggressive prostate cancer, they knew they needed to understand how this genetic alteration was driving cancer and how to ...
Oct 4, 2024
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Study unveils the role of gamma-delta T cells in cancer immunology
A new study published in Cell Reports Medicine reveals critical insights into the role of gamma-delta T cells across 33 cancer types, shedding light on their potential as clinical biomarkers and therapeutic targets in cancer ...
Oct 4, 2024
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Clinical trial finds new drug significantly extends lives of breast cancer patients
Patients with advanced HER2-positive breast cancer very often develop brain metastases. When this happens, patients have low chances of surviving the next few years with existing therapies such as surgery and radiotherapy. ...
Oct 4, 2024
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Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma
In the first study to report real-world outcomes from ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor (CAR)-T therapy for multiple myeloma, patients experienced efficacy and safety results similar to those ...
Oct 4, 2024
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Experimental blood test improves early detection of pancreatic cancer
An experimental blood test detects early-stage pancreatic cancer more effectively than other available tests, reports a new study published in Cancer Letters. The findings pave the way for further evaluation of the test in ...
Oct 4, 2024
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Colonoscopies among the young are on the rise
Colon cancers are increasing among younger Americans, so much so that experts advised in 2021 that colonoscopy screening begins at the age of 45, not 50 as had been previously recommended.
Oct 4, 2024
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Drug improves effectiveness of radiation for lung cancer that has spread to the brain
In new research, a team led by University of Cincinnati researchers has identified a potential new way to make radiation more effective and improve outcomes for patients with lung cancer that has spread to the brain. The ...
Oct 4, 2024
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New imaging technique accurately detects aggressive kidney cancer
A new study led by investigators from the UCLA Health Jonsson Comprehensive Cancer Center has demonstrated a new, non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma, the most common form ...
Oct 3, 2024
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Study ties diabetes and obesity to increased risk of liver cancer relapse
Hepatocellular carcinoma, a type of liver cancer associated with hepatitis infections, is known to have a high recurrence rate after cancer removal. Recent advances in antiviral therapy have reduced the number of patients ...
Oct 3, 2024
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Scientists decode key mutation in many cancers, pointing to expanded role of RNA in human gene expression
Inside every cell, inside every nucleus, your continued existence depends on an incredibly complicated dance. Proteins are constantly wrapping and unwrapping DNA, and even minor missteps can lead to cancer. A new study from ...
Oct 2, 2024
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Banning tobacco sales among young people could prevent 1.2 million lung cancer deaths, study suggests
Creating a generation of people who never smoke could prevent 1.2 million deaths from lung cancer globally, according to a study led by researchers from the University of Santiago de Compostela, the International Agency for ...
Oct 2, 2024
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Curbing blood cancers by teaching immune cells to kill mutant stem cells
Blood stem cells, which give rise to all of our blood cell types, undergo a quality assurance process after they're born. As the lab of Leonard Zon, MD, director of the Stem Cell Research program at Boston Children's, has ...
Oct 2, 2024
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Researchers develop insights into KRAS mutations in pancreatic cancers
A common mutation in the KRAS gene is associated with improved overall survival in pancreatic ductal adenocarcinoma (PDAC) compared with other variants, in part because the mutation appears to lead to less invasiveness and ...
Oct 2, 2024
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Clinical trial examines standard vs. extended lymph node removal for muscle-invasive bladder cancer
Final results from the SWOG S1011 randomized Phase III clinical trial, published in the New England Journal of Medicine, indicate patients undergoing surgery for localized muscle-invasive bladder cancer derive no significant ...
Oct 2, 2024
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New genetic testing pathways could ensure patients get personalized BRCA-linked cancer treatments
Scientists have developed a new clinical pathway for testing for the cancer-causing faults in the BRCA gene that could ensure patients get the right treatment and boost the number of people who get tested.
Oct 2, 2024
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Researchers propose a new treatment for brain metastasis based on immunotherapy
Researchers at the Spanish National Cancer Research Center (CNIO) propose a new treatment for brain metastases that respond poorly, or not at all, to immunotherapy, and provide a biomarker to predict in which cases it should ...
Oct 2, 2024
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Gene activation linked to severity of a rare lung cancer
Pulmonary carcinoids are rare tumors of the lung with extremely different clinical courses. In many patients, they behave like benign tumors; surgical removal of the tumor leads to a complete cure. However, some patients ...
Oct 2, 2024
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Olanzapine, prochlorperazine both alleviate refractory chemo-related nausea
Olanzapine may be better than prochlorperazine for reducing refractory nausea in patients with breast cancer starting a high/moderate emetogenic chemotherapy regimen, according to a study presented at the American Society ...
Oct 2, 2024
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2023 cisplatin shortage tied to use of alternatives for head, neck cancer
The 2023 cisplatin shortage led to a shift in utilization to alternative therapies for head and neck cancer (HNC), resulting in significant cost increases, according to a study presented at the American Society of Clinical ...
Oct 2, 2024
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How music can help boost cognition in cancer patients and COVID-19 survivors
In a first-of-its-kind study, University of South Florida researchers are finding that music can help boost cognition in patients undergoing chemotherapy. In partnership with Moffitt Cancer Center, Jennifer Bugos, USF professor ...
Oct 2, 2024
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Researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy
A Cleveland Clinic-led research collaboration between Timothy Chan, MD, Ph.D., Chair of Cleveland Clinic's Global Center for Immunotherapy, and Bristol Myers Squibb has published the most comprehensive overview to date of ...
Oct 1, 2024
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Hereditary colorectal cancer: Researchers reclassify a large proportion of leading gene variants as benign
The genetic confirmation of a suspected diagnosis of hereditary colorectal cancer is of great importance for the medical care of affected families. However, many of the variants identified in the known genes cannot yet be ...
Oct 1, 2024
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