Unexpected immune response may hold key to long-term cancer remission
Results from a preclinical study in mice led by EPFL, and a collaborative clinical study in patients show that the type 2 immune response—associated with parasitic infection and thought to play a negative role in cancer ...
20 hours ago
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Scientists develop CAR-T cells to target glioblastoma while sparing healthy tissue
Scientists at UNIGE and HUG have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue.
21 hours ago
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Genetic mutations in HRAS, KRAS genes linked to childhood cancers
Hereditary changes in genes are often the cause of rare diseases. For example, disease-causing gene variants (PVs) in the HRAS gene cause Costello syndrome and PVs in the KRAS gene cause Noonan syndrome and cardio-facio-cutaneous ...
14 hours ago
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Protein discovery advances quest for treatment for age- and cancer-related muscle degeneration
With the global population aging rapidly, sarcopenia, a condition that affects millions of older adults and severely diminishes their quality of life, is emerging as an urgent public health issue. Now, a new discovery by ...
21 hours ago
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Treatment-free remission for chronic myeloid leukemia
Leukemias are cancers of the blood cells. Chronic myelogenous leukemia (CML) is an uncommon type of cancer of the bone marrow, which produces blood cells. "Myelogenous" refers to the type of blood cells this leukemia affects. ...
23 hours ago
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Saving time with AI-generated treatment plans for breast cancer
Drawing in the organs of individual breast cancer patients and then creating precise radiation plans appears to be faster by using artificial intelligence (AI) models. That way, it remains just as reliable and accurate. It ...
16 hours ago
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AI could predict breast cancer risk via 'zombie cells'
Women worldwide could see better treatment with new AI technology, which enables better detection of damaged cells and more precisely predicts the risk of getting breast cancer, shows new research from the University of Copenhagen.
Sep 25, 2024
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Engineers use bioprinted blood vessels to model deadly brain tumors
Glioblastoma is a brain cancer with very poor survival outcomes. Most drugs can't cross the blood-brain barrier, which means that unlike other cancers, there just aren't that many therapies available for brain tumors.
Sep 25, 2024
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Promising drug combo targets aggressive bladder cancers
A new study in mice by researchers at the Herbert Irving Comprehensive Cancer Center (HICCC) has identified a promising drug combination for the treatment of muscle-invasive bladder cancer. Rosiglitazone plus trametinib worked ...
Sep 25, 2024
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Combination treatment improves response to immunotherapy for lung cancer, mouse study shows
Researchers at the Francis Crick Institute, in collaboration with Revolution Medicines, have tested a combination of treatments in mice with lung cancer and shown that these allow immunotherapies to target non-responsive ...
Sep 25, 2024
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Tumor-specific antibodies able to detect melanoma in its earliest stages, new study shows
Innovative research has unveiled promising advancements in melanoma detection, which could significantly enhance diagnosis and prognosis by identifying the disease at its earliest, most treatable stages.
Sep 25, 2024
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Study helps predict how long it will take for testosterone to return to normal after prostate cancer treatment
A study led by researchers from the UCLA Health Jonsson Comprehensive Cancer Center sheds light on testosterone recovery following androgen deprivation therapy (ADT) in men undergoing radiotherapy for prostate cancer, providing ...
Sep 25, 2024
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Is comprehensive genetic testing worth it for patients with cancer?
Comprehensive gene panel testing, one of the exciting new tools in cancer diagnostics, warrants greater scrutiny—as does a federal program aimed at speeding up the review process for proposed new medical technologies. Those ...
Sep 25, 2024
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Ru5 identified as potent antitumor agent targeting mitochondrial ATPase
A research team identified Ru5 as a potent antitumor agent by screening a panel of ruthenium(II) polypyridine complexes containing β-carboline derivatives as ligands. By employing a photoaffinity tag and utilizing the photoaffinity-based ...
Sep 25, 2024
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Analytical tool quantifies cancer's ability to shape-shift
A powerful new analytical tool offers a closer look at how tumor cells "shape-shift" to become more aggressive and untreatable, as shown in a study by researchers at Weill Cornell Medicine and the New York Genome Center.
Sep 24, 2024
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Researchers publish critical examination of new brain tumor drug
Two researchers from the Icahn School of Medicine at Mount Sinai recently published their critical evaluation of a new brain tumor medicine in the journal Nature Reviews Clinical Oncology.
Sep 24, 2024
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Research identifies nearly 200 potential breast carcinogens in food packaging materials
Researchers from the Food Packaging Forum identify and discuss nearly 200 potential breast carcinogens that have been detected in food contact materials (FCMs) on the market. Many nations have food contact material legislation ...
Sep 24, 2024
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Clinical trial results show low-intensity therapy can achieve positive outcomes for certain pediatric leukemia subtypes
Clinical trial results from St. Jude Children's Research Hospital demonstrate the benefits of using genomics and early treatment response to guide risk classification of children with B-cell acute lymphoblastic leukemia (B-ALL).
Sep 24, 2024
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Risk model identifies advanced cancer trial patients at highest risk for acute care use
Investigators from the SWOG Cancer Research Network have developed and validated a risk prediction model for identifying which patients with advanced cancer who are enrolled in clinical trials are at highest risk for unplanned ...
Sep 24, 2024
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Analysis of 2021 data shows new cancer diagnoses did not rebound as expected following pandemic
Cancer incidence trends in 2021 largely returned to what they were before the COVID-19 pandemic, according to a study by researchers at the National Institutes of Health (NIH). However, there was little evidence of a rebound ...
Sep 24, 2024
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Measurable residual disease results after consolidation therapy predictive of relapse in pediatric leukemia
For children with acute lymphoblastic leukemia (ALL), measurable residual disease (MRD) after the end of first consolidation (EOC) can be used to predict the need for subsequent MRD measurements, according to a study published ...
Sep 24, 2024
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Financial hardship common in patients with cancer
Nearly half of patients with cancer experience some level of financial hardship (FH), according to a study published online Aug. 15 in JCO Oncology Practice.
Sep 24, 2024
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A microarray-based high-throughput in situ tagged immunoprecipitation sequencing technology for diffuse midline glioma
Diffuse midline glioma (DMG) is a highly aggressive and fatal pediatric high-grade glioma that primarily affects critical regions of the central nervous system, such as the pons, thalamus, and spinal cord. Due to the high ...
Sep 24, 2024
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