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Oncology & Cancer news
Oncology & Cancer
HLA-DRB1 molecule offers potential target for CAR therapy in relapsed acute myeloid leukemia post-transplantation
One main goal of anti-cancer therapies is to kill tumor cells without affecting the surrounding normal cells. Therefore, many drugs are designed to target tumor-specific antigens, which are molecules only expressed by cancer ...
10 minutes ago
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Oncology & Cancer
High-fat diet promotes breast cancer metastasis in animal models
Obesity is associated with an increased risk of developing breast cancer, and a greater probability for the cancer to spread to other organs. But the causes of this association are still not well understood. Researchers at ...
11 hours ago
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When it comes to obesity-related cancers, where you shop for food matters
Obesity is at epidemic proportions in the United States where more than 40% of adults are obese and more than 70% are overweight. One common policy intervention to tackle this urgent issue is to try to improve diet quality ...
3 hours ago
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Lung cancer screening lags behind breast and colorectal screenings
Lung cancer screening has the potential to catch lung cancer early and save lives—but only if people get screened. Although lung cancer screening is recommended in the U.S. for certain individuals with a history of smoking, ...
3 hours ago
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Researcher uncovers how dietary fat may fuel cancer growth: Q&A
Estela Jacinto, a professor of biochemistry and molecular biology at Rutgers Robert Wood Johnson Medical School, has been studying a crucial pathway for human cell growth and metabolism for more than two decades.
9 hours ago
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Scientists identify key protein driving ovarian cancer spread
A new study has identified the protein ADAMTS5 as playing a crucial role in the spread of ovarian cancer cells, offering a potential new target for future treatments.
4 hours ago
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Targeting FGFR2 may prevent or delay some KRAS-mutated pancreatic cancers
In a recent study, precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS mutations had higher-than-normal expression of the FGFR2 protein, and FGFR2 inactivation delayed KRAS-mutated ...
3 hours ago
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Combination approach to advanced cancer could improve survival
An international team of researchers, including experts from the University of Adelaide, has found genomic testing and targeted therapies for patients with advanced cancer could improve survival rates by up to 40%.
8 hours ago
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Mutated blood cells define clinical risks in Langerhans cell histiocytosis
A nationwide team led by researchers at Baylor College of Medicine, Texas Children's Hospital and UPMC Children's Hospital of Pittsburgh has proposed a major revision to how Langerhans cell histiocytosis (LCH) is diagnosed ...
8 hours ago
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Researchers explore the high incidence of colorectal cancer in Appalachian Kentucky
Researchers at the University of Kentucky analyzed different factors that could explain the high mortality rates of colorectal cancer in Appalachian Kentucky.
4 hours ago
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Common photosensitizing drugs increase skin cancer risk, study indicates
Some commonly prescribed photosensitizing drugs increase skin cancer risk, according to a study published online March 18 in Photodermatology, Photoimmunology & Photomedicine.
9 hours ago
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Liver transplants offer new hope for colorectal cancer patients with liver metastasis
Liver transplants are becoming a new treatment option for certain colorectal cancer patients whose cancer has spread to their liver and are ineligible for other surgical options. This innovative approach is providing hope ...
9 hours ago
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Video: Liver transplant for patients with advanced colorectal cancer
Colorectal cancer is the fourth-most-common cancer in the U.S. and the second deadliest. One in 5 patients is diagnosed with metastatic disease, meaning the colorectal cancer has spread beyond the colon, often to the liver. ...
5 hours ago
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Low levels of a single enzyme influence pathway to malignancy in colorectal cancer, scientists find
The transformation of healthy cells into invasive colorectal tumors is an extraordinarily complex process involving numerous molecular mechanisms, according to cancer biologists in China who have discovered that low levels ...
Advancements in ctDNA detection promise improved lymphoma outcomes
A research team led by Prof. Gu Hongcang from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has published a comprehensive systematic review on circulating tumor DNA (ctDNA) technologies and their ...
23 hours ago
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Omega-6 fatty acid promotes the growth of an aggressive type of breast cancer, study finds
Linoleic acid, an omega-6 fatty acid found in seed oils such as soybean and safflower oil, and animal products including pork and eggs, specifically enhances the growth of the hard-to-treat "triple negative" breast cancer ...
Apr 1, 2025
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Combination immunotherapy shrinks a variety of metastatic gastrointestinal cancers in clinical trial
A new form of tumor infiltrating lymphocyte (TIL) therapy, a form of personalized cancer immunotherapy, dramatically improved the treatment's effectiveness in patients with metastatic gastrointestinal cancers, according to ...
Apr 1, 2025
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Machine learning helps predict immunotherapy response in lymphoma patients
Researchers with City of Hope and Memorial Sloan Kettering (MSK) Cancer Center have created a tool that uses machine learning to assess a non-Hodgkin lymphoma (NHL) patient's likely response to chimeric antigen receptor (CAR) ...
Apr 1, 2025
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Proteomics and chicken eggs: A novel path to match young cancer patients with the right drugs
A pan-Canadian team has developed a new way to quickly find personalized treatments for young cancer patients, by growing their tumors in chicken eggs and analyzing their proteins.
Apr 1, 2025
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Preventable pediatric cancer mortality surges in areas of armed conflict, exceeding rates in non-conflict regions
More than half of all pediatric cancer deaths worldwide occur in regions of armed conflict, according to a new study led by investigators from St. Jude Children's Research Hospital, Duke University and other collaborators. ...
Apr 1, 2025
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Awareness grows of cancer risk from alcohol consumption, survey finds
Public awareness of the link between drinking alcohol and an elevated risk of cancer has grown since last fall, with more than half of Americans now saying that regularly consuming alcohol increases your chances of later ...
Apr 1, 2025
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SOX9 as a prognostic marker in gastric adenocarcinoma
Gastric cancer (GC) is a leading cause of cancer-related deaths worldwide, with more than one million new diagnoses annually. Unfortunately, many cases are detected at advanced stages due to the lack of clear early symptoms, ...
Apr 1, 2025
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Nanoparticles extend glioblastoma survival in phase one trial
Despite decades of research to develop effective treatments, the median survival for glioblastoma—the most common malignant primary brain tumor in adults—is just 15–18 months after diagnosis. One reason for this grim ...
Apr 1, 2025
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Cancer cells 'hacked' to expose themselves to immune attack
When your social media account starts spewing out nonsensical or threatening status updates, it's safe to assume that it has been hacked and must be shut down.
Mar 31, 2025
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How smoking and drinking alcohol causes cancer: Scientists uncover unique patterns of DNA damage
Scientists have revealed exactly how tobacco smoke damages DNA to drive the development of different types of head and neck cancer, a finding that could unlock new treatments and prevention strategies.
Mar 31, 2025
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