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Oncology & Cancer news
Oncology & Cancer
What is mantle cell lymphoma? The 'rare and fast-moving' cancer explained
Beloved Australian actor, Magda Szubanski, has revealed she's been diagnosed with a "very rare, very aggressive, very serious" blood cancer called mantle cell lymphoma.
17 hours ago
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Oncology & Cancer
Scientists pioneer promising treatment derived from cactus-like plant for intractable cancer pain
National Institutes of Health (NIH) scientists report that a first-in-human clinical trial of a new therapy based on the plant-derived molecule resiniferatoxin (RTX) shows that it is a safe and effective agent for pain control ...
May 30, 2025
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Small molecule inhibitors restore normal BRAF structure, offering insight into cancer-causing mutations
Researchers led by Université de Montréal pathology and cell-biology professor Marc Therrien have identified major structural changes that enable the BRAF protein to escape control and mimic its activation, giving it strong ...
May 30, 2025
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Innovative immunotherapy shows promise against aggressive T cell cancers
A new type of immunotherapy that targets aggressive blood cancers shows promising results alongside manageable side effects, according to the results of an international Phase I/II clinical trial led by researchers at Washington ...
May 30, 2025
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Triple therapy regimen significantly improves survival in BRAF V600E-mutated metastatic colorectal cancer
First-line treatment with the triplet combination of encorafenib, cetuximab and mFOLFOX6 significantly improved survival compared to the standard of care in patients with BRAF V600E-mutated metastatic colorectal cancer, according ...
May 30, 2025
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Therapeutic target could prevent chronic gut inflammation from turning into cancer
Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic predisposition and certain factors ...
May 30, 2025
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Who should be screened for skin cancer?
Skin cancer is the most common cancer in the U.S. More than 6 million adults are treated for it each year, says Dr. Michael Colgan, a Mayo Clinic Health System dermatologist in Eau Claire, Wisconsin.
May 30, 2025
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HER3-targeted antibody-drug conjugate shows promise for treatment-resistant solid tumors
A new targeted cancer drug, DB-1310, is showing early signs of effectiveness in patients with advanced solid tumors that have not responded to standard treatments, particularly those with EGFR-mutant non-small cell lung cancer ...
May 30, 2025
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New app may help caregivers of people getting a bone marrow transplant
A new study by investigators from Mass General Brigham showed that a new app they created can help improve the quality of life for caregivers of patients undergoing bone marrow transplant (BMT). The researchers conducted ...
May 30, 2025
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Alcohol-fueled cancer deaths are on the rise in the US
A new study led by experts at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, is the first to look at trends over time in alcohol-linked cancer mortality across the United ...
May 30, 2025
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Routine breast cancer screening can bring better outcomes for patients
Researchers have discovered that, compared to breast cancer that is symptom-detected, patients with breast cancer detected via routine screening mammography are more likely to have improved clinical outcomes, according to ...
May 30, 2025
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Number of cancer survivors in the US reaches 18.6 million—projected to exceed 22 million by 2035
The number of people living with a history of cancer in the United States is estimated at 18.6 million as of January 1, 2025 and projected to exceed 22 million by 2035, according to a new report, "Cancer Treatment and Survivorship ...
May 30, 2025
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Massachusetts brain tumor cluster: Nurses not satisfied with Newton-Wellesley study
A nurses' union isn't satisfied with a Mass General Brigham investigation that found the brain tumor cluster at Newton-Wellesley Hospital is not connected to working conditions.
May 30, 2025
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New standard of care emerges for multiple myeloma
A new four-drug combination is highly effective and safe in patients with newly diagnosed multiple myeloma, according to data presented at the annual meeting of the American Society of Clinical Oncology (ASCO), held May 30 ...
May 30, 2025
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People with disabilities are dying from preventable cancers, study shows
People with disabilities are missing out on screening programs that could help detect cancer early, and after diagnosis, are less likely to survive, our study shows.
May 30, 2025
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Bladder cancer treatment reprograms bone marrow to boost immune system's cancer-fighting ability
More than three decades ago, the U.S. Food and Drug Administration (FDA) approved Bacillus Calmette-Guérin (BCG) as the first immunotherapy against cancer. And it is still used today to treat early-stage bladder cancer.
May 29, 2025
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Next-gen biobattery shrinks tumor, paving way for drug-free cancer treatments
A pioneering biobattery has been shown to reduce tumor growth in the body and could hold the key to a new drug-free immunotherapy treatment in cancer patients.
May 29, 2025
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Personalized cancer model predicts patient-specific gene behavior, potentially improving survival outcomes
Carnegie Mellon University researchers are using personalized models to decode how cancer behaves in individual patients—revealing hidden subtypes, improving survival predictions and charting a new course for precision ...
May 29, 2025
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Genetics and therapy type determine second cancer risk after childhood treatment, study finds
Scientists at St. Jude Children's Research Hospital have found that genetics and type of cancer treatment contribute most to a survivor's risk of a second cancer.
May 29, 2025
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Potent CDK9 inhibitor shows promise for overcoming drug resistance in hematological malignancies
A research team has developed a new class of compounds that effectively inhibit both wild-type CDK9 and its drug-resistant mutant form, offering a promising strategy for treating hematological malignancies.
May 29, 2025
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Machine learning algorithm brings long-read sequencing to the clinic
Long-read sequencing technologies analyze long, continuous stretches of DNA. These methods have the potential to improve researchers' ability to detect complex genetic alterations in cancer genomes. However, the complex structure ...
May 29, 2025
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Scientists find promise in a new peptide drug to combat a deadly brain cancer
A lab-designed molecule developed and extensively studied by scientists with Virginia Tech's Fralin Biomedical Research Institute at VTC could represent a breakthrough in slowing tumor recurrence in glioblastoma, an aggressive ...
May 29, 2025
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Childhood kidney cancer has millions of genetic changes, opening door to possible treatments
Researchers have uncovered that some childhood cancers have a substantially higher number of DNA changes than previously thought, changing the way we view children's tumors and possibly opening up new or repurposed treatment ...
May 29, 2025
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Study sheds light on enzyme's role in driving lymphoma growth
A study led by University of Cincinnati Cancer Center researchers sheds new light on the mechanisms by which a major oncogene promotes and sustains lymphoma development and progression, paving the way for novel targeted therapies.
May 29, 2025
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Poorly functioning blood vessels linked to muscle wasting in cancer
A dysfunction in muscle blood vessels could be to blame for the weak muscles and weight loss that most cancer patients experience, according to a new study from University of Illinois Chicago researchers.
May 29, 2025
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