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Oncology & Cancer news

Oncology & Cancer

Clinical cancer research in the US is increasingly dominated by pharmaceutical industry sponsors, study finds

Researchers at Fred Hutch Cancer Center identified a substantial increase over the past decade in the proportion of patients with cancer in the U.S. who participate in pharmaceutical industry sponsored clinical trials compared ...

Oncology & Cancer

Study finds estrogens play a hidden role in cancers, inhibiting a key immune cell

Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study by Duke Cancer Institute researchers unexpectedly finds that estrogens play a role in fueling the growth of breast ...

Oncology & Cancer

Genetic mutations in HRAS, KRAS genes linked to childhood cancers

Hereditary changes in genes are often the cause of rare diseases. For example, disease-causing gene variants (PVs) in the HRAS gene cause Costello syndrome and PVs in the KRAS gene cause Noonan syndrome and cardio-facio-cutaneous ...

Oncology & Cancer

Treatment-free remission for chronic myeloid leukemia

Leukemias are cancers of the blood cells. Chronic myelogenous leukemia (CML) is an uncommon type of cancer of the bone marrow, which produces blood cells. "Myelogenous" refers to the type of blood cells this leukemia affects. ...

Oncology & Cancer

Saving time with AI-generated treatment plans for breast cancer

Drawing in the organs of individual breast cancer patients and then creating precise radiation plans appears to be faster by using artificial intelligence (AI) models. That way, it remains just as reliable and accurate. It ...

Oncology & Cancer

AI could predict breast cancer risk via 'zombie cells'

Women worldwide could see better treatment with new AI technology, which enables better detection of damaged cells and more precisely predicts the risk of getting breast cancer, shows new research from the University of Copenhagen.

Medical research

Promising drug combo targets aggressive bladder cancers

A new study in mice by researchers at the Herbert Irving Comprehensive Cancer Center (HICCC) has identified a promising drug combination for the treatment of muscle-invasive bladder cancer. Rosiglitazone plus trametinib worked ...

Oncology & Cancer

Analytical tool quantifies cancer's ability to shape-shift

A powerful new analytical tool offers a closer look at how tumor cells "shape-shift" to become more aggressive and untreatable, as shown in a study by researchers at Weill Cornell Medicine and the New York Genome Center.

Oncology & Cancer

Researchers uncover how colorectal cancer cells colonize the liver

In cases where cancer is fatal, 9 out of 10 times the culprit is metastasis. This is when the primary tumor has sent out cells, like seeds, and invaded other organs of the body. While medicine has made great progress in treating ...

Oncology & Cancer

Blood test may guide use of multiple myeloma immunotherapy

A simple blood test that measures the number of lymphocytes, a type of white blood cell in the body, may predict whether people who have relapsed multiple myeloma are going to respond well to CAR-T immunotherapy, according ...

Oncology & Cancer

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, ...

Oncology & Cancer

Prostate cancer blood test equally effective across ethnic groups

The Stockholm3 blood test, developed by researchers at Karolinska Institutet, is equally effective at detecting prostate cancer in different ethnic groups, a new paper published in the Journal of Clinical Oncology reports. ...