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Oncology & Cancer news
Oncology & Cancer
Weight gain after breast cancer development tied to heart failure risk
For women with newly diagnosed invasive breast cancer (BC), weight gain is associated with an increased risk for heart failure, according to a research letter published online Jan. 9 in JAMA Oncology.
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Oncology & Cancer
'Explant' technique predicts a tumor's responsiveness to breast cancer treatment
Cancer researchers at the University of Leicester have developed a technique that could predict how well some breast cancer patients will respond to chemotherapy and antibody-directed cancer treatments.
Jan 10, 2025
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A battle of rafts: How molecular dynamics in CAR T cells explain their cancer-killing behavior
A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor (CAR) T cells kill cancer.
Jan 10, 2025
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Lung cancer trial reveals 40% drop in deaths using biomarker testing
New research from the University of St Andrews School of Medicine has found that biomarker testing in individuals at risk of lung cancer led to a major reduction in deaths.
Jan 10, 2025
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Super-resolution microscopy shows how therapeutic antibodies work against cancer cells
In blood cancers such as chronic lymphocytic leukemia, B cells of the immune system multiply uncontrollably. One form of therapy involves labeling the CD20 protein on the surface of the B cells with customized antibodies. ...
Jan 10, 2025
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Why new precision oncology treatments benefit patients of some ancestries more than others
Nearly half of all new cancer drugs approved by the U.S. Food and Drug Administration (FDA) over the past quarter-century have received that approval based on their ability to target genetic changes driving tumor growth.
Jan 10, 2025
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Air pollution emerges as a growing concern in risk factors linked to lung cancer deaths
Even though lung and related cancer deaths decreased in the world's 10 most populous countries from 1990 to 2019, these positive statistics do not address trends in mortality linked to tobacco use, air pollution and asbestos ...
Jan 10, 2025
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Tongue cancer organoids reveal secrets of chemotherapy resistance
Oral cancer is an increasingly prevalent disease worldwide, with over 300,000 new cases diagnosed each year. Among oral cancers, tongue cancer (TC) is the most common type and often carries a poor prognosis.
Jan 10, 2025
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New drug for prostate cancer patients in clinical trials
Prostate cancer that has become resistant to hormone therapy could be treated using a new drug that is currently in clinical trials for ovarian and bile duct cancer, according to research published in the journal Clinical ...
Jan 10, 2025
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AI can enhance cervical cancer detection with medical image recognition
Cervical cancer remains a major health threat for women globally, with the highest incidence in developing nations. Despite the availability of preventive measures, challenges such as limited health care resources and inadequate ...
Jan 10, 2025
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Alcohol raises colorectal cancer risk while calcium protects, study finds
Researchers from the Cancer Epidemiology Unit at the University of Oxford, along with collaborators from international institutions, found significant associations between diet and colorectal cancer risk. Examining data from ...
Scientists reveal genetic drivers of metastasis across multiple cancer types
Cancer metastasis—the spread of cancer to other organs—is the leading cause of death among cancer patients. Researchers have now uncovered a "genetic signature" of 177 genes shared across multiple cancer types that drives ...
Jan 9, 2025
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Kidney cancer study identifies factors for exceptional response to immunotherapy
Metastatic clear cell renal cell carcinoma (mccRCC), an aggressive type of kidney cancer, has historically presented limited treatment options. Immune checkpoint inhibitors, a form of immunotherapy, can lead to exceptional, ...
Jan 9, 2025
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Combination treatment for liver cancer significantly improves progression-free survival in global trial
Researchers at Mount Sinai have made a breakthrough in treating a type of liver cancer called hepatocellular carcinoma (HCC). This research, led by Josep M. Llovet, MD, Ph.D., Professor of Medicine (Liver Diseases) at the ...
Jan 9, 2025
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Drug resistance study reveals mechanisms that enable lung cancer recurrence
A recent study uncovers how drug-resistant cancer cells induce changes in the tumor microenvironment. This phenomenon promotes cancer recurrence and explains why initially effective targeted therapies can lose their efficacy ...
Jan 9, 2025
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ORACLE lung cancer test predicts survival in early stages better than current methods
Researchers at the Francis Crick Institute, the UCL Cancer Institute and UCLH have shown that a test called ORACLE can predict lung cancer survival at the point of diagnosis better than currently used clinical risk factors. ...
Jan 9, 2025
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AI platform identifies which patients are likely to benefit most from a cancer clinical trial
A study led by Winship Cancer Institute of Emory University and Abramson Cancer Center of the University of Pennsylvania researchers demonstrates that a first-of-its-kind platform using artificial intelligence (AI) could ...
Jan 9, 2025
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Clinical trial shows 'Shared Care' model safe for patients after donor stem cell transplant
Patients undergoing a donor stem-cell transplant for leukemia or other blood-related cancer require months of specialized follow-up care, traditionally delivered at the center where they received their transplant—often ...
Jan 9, 2025
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Transplant of frozen testicular tissue after chemotherapy during childhood provides hope for fertility restoration
In boys who, before starting puberty, undergo radical treatments that can affect their fertility, testicular tissue can be preventively removed and frozen. This is done to preserve testicular stem cells, the precursors of ...
Jan 9, 2025
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Nonadherence to cancer screening varies by screening type
Nonadherence to cancer screening varies by screening type and sex, according to a study published in JAMA Network Open.
Jan 9, 2025
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Talquetamab plus teclistamab shows promise in multiple myeloma
For patients with relapsed or refractory multiple myeloma, talquetamab plus teclistamab shows response in a high percentage of patients and a higher incidence of grade 3 or 4 infections than with either therapy alone, according ...
Jan 9, 2025
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New tool puts reproductive risk for BRCA carriers into perspective
"I just wish someone had told me this was a possibility." Kara Maxwell distinctly remembers the moment she heard those words eight years ago from the mother of a child with Fanconi anemia (FA). Maxwell met her at a conference ...
Jan 9, 2025
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Study identifies TBK1 as key to overcoming CAR T resistance
Russell W. Jenkins, MD, Ph.D., a physician investigator in the Krantz Family Center for Cancer Research at the Mass General Cancer Center and an assistant professor of Medicine at Harvard Medical School, is senior author ...
Jan 9, 2025
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Improving cancer risk assessment and patient care: Researchers resolve uncertainty in BRCA2 testing
Findings from a multi-institutional, international study led by researchers from the Mayo Clinic Comprehensive Cancer Center have significantly advanced the understanding of genetic alterations in the BRCA2 gene, a key player ...
Jan 8, 2025
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Unique AI predicts cancer prognoses and responses to treatment by combining data from medical images with text
The melding of visual information (microscopic and X-ray images, CT and MRI scans, for example) with text (exam notes, communications between physicians of varying specialties) is a key component of cancer care. But while ...
Jan 8, 2025
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