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Oncology news

New drug combination may help treat advanced prostate cancer

About 1 in 8 men are diagnosed with prostate cancer during their lifetime. Although many survive, it can develop into metastatic disease.

Drugs developed in China reaching international markets, research finds

China has become an increasingly important contributor to pharmaceutical development, but comparatively little attention has been paid to how successfully medicines developed in China have entered major international markets.

Exploring precision medicine for pancreatic cancer

Imagine if, before starting cancer care, doctors could rapidly identify the most effective chemotherapy, immunotherapy or combination to personalize treatment for a loved one's hard-to-treat pancreatic cancer and improve ...

A unified framework to explain one of cancer's major drivers

In a rare pair of papers published back-to-back in the journal Genes & Development, research teams led by senior author Anindya Bagchi, Ph.D., associate professor in the Cancer Genome and Epigenetics Program at Sanford Burnham ...

How 'undead' cells trigger cancer-promoting inflammation

Stopping tumor growth is only half the battle. Rather than killing tumor cells, many cancer therapies can only push them into cellular senescence, a state in which cells stop dividing but do not die. These "undead" cells ...

How highly aggressive colon cancer evades the immune system

Researchers from the German Cancer Research Center (DKFZ) and the HI-STEM Stem Cell Institute have identified a previously unknown mechanism by which a particularly aggressive form of colon cancer evades the immune system.

Math and medicine join forces to solve a cancer mystery

Immunotherapy has transformed outcomes for many cancer patients. Unlike conventional treatments, these therapies do not attack tumors directly. Instead, they enable the body's immune system to identify and kill cancer cells ...

Newly found 'immune organ' inside skull directs brain defense

Researchers at Washington University School of Medicine in St. Louis have discovered lymph node-like structures in the skull bone marrow of mice for the first time and demonstrated that they act as rapid first responders ...

New biobank of tumor models reveals cancers' weak spots

A new open resource of cancer models has enabled researchers to create the first large-scale map of the genes that cancers rely on to survive, offering new avenues for research into better and less toxic treatments for patients.

Researchers discover immune 'off switch' used by cancer cells

Mayo Clinic researchers have identified a protein that cancer cells use to shut down the body's immune response, a discovery that could help scientists develop new treatments that make cancer immunotherapies more effective.

New therapy shrinks tumors to treat lung cancer

The need for more effective lung cancer treatments is paramount, as the disease remains a leading cause of cancer deaths in the United States. New findings by a research team from the Stony Brook Cancer Center highlight a ...