Researchers develop insights into KRAS mutations in pancreatic cancers
A common mutation in the KRAS gene is associated with improved overall survival in pancreatic ductal adenocarcinoma (PDAC) compared with other variants, in part because the mutation appears to lead to less invasiveness and ...
7 hours ago
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Curbing blood cancers by teaching immune cells to kill mutant stem cells
Blood stem cells, which give rise to all of our blood cell types, undergo a quality assurance process after they're born. As the lab of Leonard Zon, MD, director of the Stem Cell Research program at Boston Children's, has ...
8 hours ago
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Clinical trial examines standard vs. extended lymph node removal for muscle-invasive bladder cancer
Final results from the SWOG S1011 randomized Phase III clinical trial, published in the New England Journal of Medicine, indicate patients undergoing surgery for localized muscle-invasive bladder cancer derive no significant ...
3 hours ago
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Scientists decode key mutation in many cancers, pointing to expanded role of RNA in human gene expression
Inside every cell, inside every nucleus, your continued existence depends on an incredibly complicated dance. Proteins are constantly wrapping and unwrapping DNA, and even minor missteps can lead to cancer. A new study from ...
9 hours ago
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Olanzapine, prochlorperazine both alleviate refractory chemo-related nausea
Olanzapine may be better than prochlorperazine for reducing refractory nausea in patients with breast cancer starting a high/moderate emetogenic chemotherapy regimen, according to a study presented at the American Society ...
6 hours ago
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Gene activation linked to severity of a rare lung cancer
Pulmonary carcinoids are rare tumors of the lung with extremely different clinical courses. In many patients, they behave like benign tumors; surgical removal of the tumor leads to a complete cure. However, some patients ...
3 hours ago
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How music can help boost cognition in cancer patients and COVID-19 survivors
In a first-of-its-kind study, University of South Florida researchers are finding that music can help boost cognition in patients undergoing chemotherapy. In partnership with Moffitt Cancer Center, Jennifer Bugos, USF professor ...
4 hours ago
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Researchers propose a new treatment for brain metastasis based on immunotherapy
Researchers at the Spanish National Cancer Research Center (CNIO) propose a new treatment for brain metastases that respond poorly, or not at all, to immunotherapy, and provide a biomarker to predict in which cases it should ...
16 hours ago
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2023 cisplatin shortage tied to use of alternatives for head, neck cancer
The 2023 cisplatin shortage led to a shift in utilization to alternative therapies for head and neck cancer (HNC), resulting in significant cost increases, according to a study presented at the American Society of Clinical ...
10 hours ago
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Researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy
A Cleveland Clinic-led research collaboration between Timothy Chan, MD, Ph.D., Chair of Cleveland Clinic's Global Center for Immunotherapy, and Bristol Myers Squibb has published the most comprehensive overview to date of ...
Oct 1, 2024
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Hereditary colorectal cancer: Researchers reclassify a large proportion of leading gene variants as benign
The genetic confirmation of a suspected diagnosis of hereditary colorectal cancer is of great importance for the medical care of affected families. However, many of the variants identified in the known genes cannot yet be ...
Oct 1, 2024
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Researchers identify new therapeutic approach to preventing cancer from spreading to the brain
In a study published in the journal Cell Reports Medicine, researchers Sheila Singh and Jakob Magolan discovered a critical vulnerability in metastatic brain cancer, which they say can be exploited with new drugs to prevent ...
Oct 1, 2024
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Precision breast cancer trial shows improved treatment by tumor subtype
Despite recent advances in the treatment of breast cancer, it remains the second leading cause of cancer death in the U.S. and worldwide. There is a continued need to improve treatment strategies and therapies that not only ...
Oct 1, 2024
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Cellular power-up: Stem cells provide T cells a lifeline as cancer champions
In a pioneering study that bridges the gap between science fiction and reality, researchers have unveiled an innovative method to enhance T and CAR-T cells—our body's natural and engineered defenders against cancer—by ...
Oct 1, 2024
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Radon, even at levels below EPA guideline for mitigation, is linked to childhood leukemia
A study of more than 700 counties across multiple U.S. states found a link between childhood leukemia and levels of decaying radon gas, including those lower than the federal guideline for mitigation. The research is published ...
Oct 1, 2024
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Scientists develop new model for ovarian cancer, with crossover to uterine cancer
Most uterine cancers have excellent five-year survival rates—up to 95% for localized cancer. Serous uterine cancer is an exception, with five-year survival rates of 35% to 50% for stage 1 or 2 cancer.
Oct 1, 2024
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Categorizing the epigenetic hallmarks that define cancer
Cancer mortality has just surpassed cardiovascular disease for the first time ever and one in two men, and one in three women, will be diagnosed with some form of the disease in the US, according to the NIH.
Oct 1, 2024
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Report explores the role alcohol plays in new cancer cases
A little bit of alcohol was once thought to be good for you. However, as scientific research advances, we're gaining a clearer picture of alcohol's effect on health—especially regarding cancer.
Oct 1, 2024
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Cardiopulmonary fitness is key for helping breast cancer patients manage post-diagnosis symptoms, say researchers
Newly diagnosed breast cancer patients often experience such symptoms as fatigue, depression and poor sleep quality, even before treatments such as chemotherapy and radiation. However, recommendations for managing symptoms ...
Oct 1, 2024
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Report: Breast cancer mortality continues three decade decline, but steeper increases in incidence for some women
The American Cancer Society (ACS) has released Breast Cancer Statistics, 2024, the organization's biennial update on breast cancer occurrence and trends in the United States.
Oct 1, 2024
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Black, white cancer patients now benefit equally from cord blood therapy
Blood cancer patients of all races who receive cord blood transplants are now living longer.
Oct 1, 2024
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Chemotherapy can be a challenging treatment—here's how to deal with some of the side-effects
Chemotherapy is a powerful cancer medication—but it can also be a very challenging treatment. It works by killing fast-growing cancer cells but kills healthy cells too, so it's important to know how to care for your body ...
Oct 1, 2024
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Researchers suggest rethinking 'cancer' label for early-stage prostate changes
A new paper in the Journal of the National Cancer Institute indicates that patients may benefit if doctors stop calling certain early-stage changes to the prostate "cancer" at all. The paper is titled "When is prostate cancer ...
Oct 1, 2024
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