A defining feature of Alzheimer's disease is the abnormal, sustained accumulation of protein aggregates such as tau inside brain cells, which disrupts the cells' normal functions. As time passes, brain cells stop working ...
Nov 2, 2026
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Parkinson's disease (PD) is a neurodegenerative condition that causes the progressive loss of dopamine-producing neurons in a brain region called the substantia nigra. Its characteristic symptoms include tremors, slowed movements, ...
Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease. ...
Sep 24, 2026
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Over the past few decades, antibody-based therapies have revolutionized modern medicine and are now widely used to treat cancer, autoimmune diseases, inflammatory disorders and even infectious diseases. Despite their success, ...
Sep 13, 2026
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The aging brain frequently harbors multiple protein pathologies that contribute to Alzheimer's, Parkinson's and other neurodegenerative diseases. But how do these problematic proteins interact with each other, and could these ...
Jul 8, 2026
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Researchers at the Icahn School of Medicine at Mount Sinai have found that patients with Parkinson's disease undergoing deep brain stimulation (DBS) show little to no Lewy pathology in the prefrontal cortex at the time of ...
Jul 2, 2026
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Studies of genetics conducted in yeast cells, human neurons, mice or other model systems often reveal networks of genes that could contribute to complex diseases, such as breast cancer, type 2 diabetes and Parkinson's disease. ...
Jun 26, 2026
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For the first time, therapeutically effective medications are now available for Alzheimer's disease. Effective symptomatic therapies also exist for Parkinson's disease; however, a prerequisite for successful treatment is ...
May 21, 2026
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Long-term exposure to smog might increase the risk of Lewy body dementia, the brain disease that CNN founder Ted Turner battled for several years before his recent death, a new study says.
May 18, 2026
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Monoclonal antibodies can block a key immune-related protein that drives the spread of brain cell damage in Parkinson's disease (PD). This protein, called glycoprotein nonmetastatic melanoma B (GPNMB), might be part of a ...
May 13, 2026
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