Researchers at UT Southwestern Medical Center have identified a key brain signaling pathway that appears to drive the substantial weight gain often associated with clozapine, a widely used antipsychotic medication. The preclinical ...
Sep 6, 2026
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A protein essential to the human body for managing energy and regulating appetite relies on a partner protein, according to new research, and the findings could help researchers better understand genetic obesity.
Dec 16, 2025
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Deficiency of the gene melanocortin 4 receptor (MC4R) is linked with obesity among adults. A recent study has found that the same deficiency also leads to surprising outcomes such as reduced risk of heart disease, lower cholesterol, ...
The obesity rate has been steadily climbing and so have scientific efforts to understand why. A new study, published in Nature Communications, takes a closer look at the genes behind body weight and how they might point toward ...
Oct 20, 2025
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Researchers at Leipzig University and Charité—Universitätsmedizin Berlin have discovered a key mechanism for appetite and weight control. It helps the brain to regulate feelings of hunger.
Sep 30, 2025
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Researchers from George Washington University have uncovered promising evidence in an animal study that shows setmelanotide, an FDA-approved medication for a rare genetic obesity disorder, may offer a pathway for treating ...
Jun 17, 2025
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Using a tool called Automated Meiotic Mapping (AMM) that was developed at UT Southwestern Medical Center, a team of researchers has identified a gene that appears to be key to regulating food intake.
Jun 6, 2025
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For the first time, large-scale DNA sequence data on three U.K. long-term birth cohorts has been released, creating a unique resource to explore the relationship between genetic and environmental factors in child health and ...
Mar 4, 2025
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Scientists discovered years ago that the hypothalamus—which helps to manage body temperature, hunger, sex drive, sleep and more—includes neurons that express the protein opsin 3 (OPN3). Far less clear, however, was what this ...
Feb 15, 2025
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Mutations in a gene called OTP cause obesity by controlling the output of another gene already targeted by an anti-obesity drug, a study led by UT Southwestern Medical Center researchers shows. The findings, reported in Science ...
Jan 16, 2025
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