UCLA researchers have uncovered a hidden weakness in some of the deadliest cancers, revealing a potential new strategy for targeting tumors that have long resisted treatment. Small cell neuroendocrine cancers, aggressive ...
Mar 23, 2026
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A new study published in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center details a therapeutic vulnerability in patients with an aggressive subtype of triple-negative breast ...
Dec 24, 2025
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A new study from Karolinska Institutet, published in Nature Communications, reveals that cyclin-dependent kinases (CDK) promote DNA replication licensing in human cells by relieving inhibitory signals from RB tumor suppressor ...
Sep 15, 2025
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Researchers at Moffitt Cancer Center have created the first genetically engineered model of lung cancer in naked mole rats, a species long thought to be resistant to cancer. The findings, published in Cancer Discovery, shed ...
Sep 8, 2025
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Researchers have identified the origin of ovarian cancer that develops in the fallopian tube, which opens doors to discovering new methods for diagnosing the disease and potential therapies.
Oct 16, 2024
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Shutting down a gene called PRMT5 stopped metastatic estrogen receptor-positive (ER+) breast cancer cells from growing after they acquired resistance to a standard therapy known as CDK4/6 inhibitors, UT Southwestern Medical ...
Apr 25, 2024
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Mutations, which occur continuously in every cell of our bodies, are a key contributor to cancer, aging, and neurodegeneration. While exposure to mutagenic chemicals, or mistakes in cellular processes during DNA replication ...
Jan 10, 2024
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Epigenetic changes can cause prostate cancer to resist treatment by switching genes on or off. One epigenetic mechanism tags genes with DNA methylation marks. This process is mediated by molecules called DNA methyltransferases. ...
Nov 15, 2023
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Despite decades of medical advances, children who develop the pediatric eye cancer retinoblastoma often lose their vision or an eye due to a lack of specific, targeted therapies and a poor molecular understanding of the cancer. ...
Oct 3, 2022
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