Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and begins in the cells lining the pancreatic duct. Accounting for more than 90% of all pancreatic cancers, PDAC is extremely difficult ...
Jan 15, 2026
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A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by investigators at Weill Cornell Medicine and the New York Genome Center.
Jan 14, 2026
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Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics. Among them, the Y220C mutation is the ninth most frequent and it creates a small crevice ...
Jan 12, 2026
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A large-scale international study, led by researchers from the Gray Faculty of Medical and Health Sciences at Tel Aviv University, has uncovered a mechanism that allows breast cancer to send metastases to the brain—a highly ...
Jan 5, 2026
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St. Jude Children's Research Hospital scientists have identified a promising combination approach to treat a rare but catastrophic pediatric brain cancer called atypical teratoid rhabdoid tumor (ATRT).
Dec 16, 2025
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In many aspects of our lives, we find meaning in the order in which events occur. We buy into myths about "middle child syndrome," talk of calm before storms, and consider it strange to start a meal with dessert.
Nov 20, 2025
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The gene p53 acts as a tumor suppressor and is often called the guardian of the genome. This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading to cancer. But when p53 ...
Nov 5, 2025
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The human body relies on precise genetic instructions to function, and cancer begins when these instructions get scrambled. When cells accumulate genetic errors over time, they can break free of the normal controls on their ...
Oct 29, 2025
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A new study from Karolinska Institutet, published in Nature Communications, reveals that cyclin-dependent kinases (CDK) promote DNA replication licensing in human cells by relieving inhibitory signals from RB tumor suppressor ...
Sep 15, 2025
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Researchers at Moffitt Cancer Center have created the first genetically engineered model of lung cancer in naked mole rats, a species long thought to be resistant to cancer. The findings, published in Cancer Discovery, shed ...
Sep 8, 2025
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