The gene p53 acts as a tumor suppressor and is often called the guardian of the genome. This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading to cancer. But when p53 ...
Nov 5, 2025
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The human body relies on precise genetic instructions to function, and cancer begins when these instructions get scrambled. When cells accumulate genetic errors over time, they can break free of the normal controls on their ...
Oct 29, 2025
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A new study from Karolinska Institutet, published in Nature Communications, reveals that cyclin-dependent kinases (CDK) promote DNA replication licensing in human cells by relieving inhibitory signals from RB tumor suppressor ...
Sep 15, 2025
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Researchers at Moffitt Cancer Center have created the first genetically engineered model of lung cancer in naked mole rats, a species long thought to be resistant to cancer. The findings, published in Cancer Discovery, shed ...
Sep 8, 2025
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University of Oxford-led research finds low-dose rapamycin functions as a genomic protector in aging human immune cells, lowering DNA damage.
Triple-negative breast cancer (TNBC), the deadliest breast cancer subtype, disproportionately affects African American women—but until now, they have been underrepresented in genomic studies aimed at identifying the genetic ...
Aug 26, 2025
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All cells in the body contain the same DNA, but different cell types express different genes; skin cells express genes for the skin, liver cells express liver genes, and so on. This coordination is crucial to help cells differentiate ...
Aug 20, 2025
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A study co-led by researchers at The Hospital for Sick Children (SickKids) and the University of Toronto's Temerty Faculty of Medicine has uncovered why some very-high-risk brain tumors are resistant to radiation—and identified ...
Aug 18, 2025
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Each cell in our bodies carries about two meters of DNA in its nucleus, packed into a tiny volume of just a few hundred cubic micrometers—about a millionth of a milliliter. The cell manages this by winding the strings of ...
Jul 25, 2025
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A University of Minnesota Medical School-led research team has discovered that a cancer signaling pathway has previously unrecognized roles in retina and brain blood vessels. The findings were recently published in Science ...
Jul 10, 2025
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