Microtubules, part of heart muscle cells' internal "skeleton," help determine how the heart changes shape under stress, and a common signaling pathway called the ERK pathway acts as a key controller of where the building ...
Jun 9, 2026
0
3
Thousands of times per year, a family's moment of joy turns to unexpected grief. A seemingly healthy infant stops smiling or making eye contact. Their limbs grow weak. The tiny child suffers seizures and breathing problems.
May 8, 2026
0
11
Amyloid beta and tau proteins compete for the same binding sites on microtubules in neurons, suggesting that displacement of tau by amyloid beta, rather than aggregation of either protein, may be the primary driver of Alzheimer's ...
Mar 17, 2026
0
10
A gene called FOXJ1 may drive resistance to taxane chemotherapy during treatment for advanced prostate cancer, according to a new study led by investigators at Weill Cornell Medicine and Beth Israel Deaconess Medical Center. ...
Mar 10, 2026
0
9
A Dartmouth study published in Nature Communications reveals that immune cells in the brain use a surprising two-step process to power their search-and-destroy missions. When immune cells rush to injury sites in the brain, ...
Jan 26, 2026
0
97
Scientists have long known that inherited neurodegenerative disorders, including Alzheimer's, Parkinson's or motor neuron disease, can be traced back to genetic mutations. However, how they cause the diseases remains unanswered.
Jan 19, 2026
0
17
A designer version of the tau protein, developed by a team led by UT Southwestern Medical Center researchers, maintains its biological function while resisting aggregation, a pathological trait linked to neurodegenerative ...
Dec 23, 2025
0
49
Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the Okinawa Institute of Science ...
Nov 5, 2025
0
29
A Northwestern Medicine study has revealed a key mechanism underlying the development of motor neuron diseases, offering new insights into potential treatment options, according to a study published in the Journal of Neuroscience.
Oct 16, 2025
0
16
Researchers at the Central Institute of Mental Health (CIMH) in Mannheim, together with international partners, have developed patient-derived brain organoids for the first time in order to better understand the rare genetic ...
Oct 15, 2025
0
16
