In response to stress or damage, cells undergo senescence and stop dividing. However, if senescent cells accumulate in tissues over the long term, chronic inflammation occurs and the risk of cancer increases. Researchers ...
Jun 3, 2026
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Switching off an enzyme that plays an important role in sugar metabolism, glycolysis, would normally be expected to cause serious problems for cells. Surprisingly, the opposite is also true: Cells can become highly resistant ...
May 30, 2026
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Ascites—the buildup of liquid in the belly—may be doing more than causing discomfort. A Duke University School of Medicine study finds this fluid helps cancer cells survive and spread—and that a decades-old cholesterol drug ...
May 11, 2026
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For decades, the relationship between fat and cancer has been treated as a question of quantity: Eat less fat, reduce your risk of developing cancer. But new research published April 29 in Cancer Discovery shows that for ...
May 1, 2026
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A new set of drugs exploit a recently revealed weakness in "zombie-like"—or senescent—cells that could lead to new treatments for cancer and age-associated diseases. The study from the MRC Laboratory of Medical Sciences (LMS) ...
Apr 24, 2026
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Researchers from Drexel University's College of Medicine have identified a critical metabolic vulnerability in breast cancer that has spread to the brain, offering a promising new therapeutic target for a disease with few ...
Apr 22, 2026
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While modern life includes many conveniences, humans are still incessantly exposed to a variety of metabolic stresses we have never experienced before. Our immune systems are constantly trying to protect us, and CD8⁺ T cells ...
Apr 20, 2026
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The correlation between smoking and neurodegeneration is well-documented, with one study from 2011 finding that heavy smoking in midlife was associated with a greater than 100% increase in risk of dementia, Alzheimer's and ...
Apr 8, 2026
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In a preclinical study published in Cancer Research, researchers from the University of Texas MD Anderson Cancer Center have identified one way that lung cancer becomes resistant to radiation therapy and then developed a ...
Apr 8, 2026
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Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can be harnessed for cancer therapy. Given that more than 95% of pancreatic ductal adenocarcinomas (PDACs) harbor ...
Apr 2, 2026
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