Scientists have discovered tumors can tap a nontraditional pathway to acquire lipoproteins—molecules that transport fat in blood—which enriches cancer cells with an antioxidant shield to survive stress, according to new research ...
Jun 12, 2025
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Northwestern Medicine scientists have developed a promising approach to killing treatment-resistant cancer cells by exploiting their hidden metabolic vulnerabilities, according to a study published in the Proceedings of the ...
Jun 5, 2025
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A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL), the most common cancer in childhood and one that can be particularly difficult ...
May 20, 2025
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In a comprehensive research study, scientists have uncovered a previously unknown mechanism explaining how neurons survive botulinum neurotoxin type A (BoNT/A) exposure, despite the toxin's powerful ability to block neurotransmission.
May 20, 2025
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Current anticancer treatments essentially target the primary tumor cells that proliferate quickly, but do not effectively eliminate specific cancer cells able to adapt to existing treatments and which exhibit high metastatic ...
May 7, 2025
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The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or programmed cell death, is also necessary ...
May 1, 2025
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A Ludwig Cancer Research study has identified a specific mode of fat uptake by immune cells within tumors that serves as a metabolic checkpoint against anti-cancer immune responses. Harnessing that insight, researchers led ...
Apr 28, 2025
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A study has uncovered that iron orchestrates the activation of two damaging cell death pathways—ferroptosis and necroptosis—early in ischemic stroke recovery, exacerbating brain injury. This discovery sheds light on how iron ...
Mar 4, 2025
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One particular challenge in the treatment of cancer is therapy resistance. An international research team has now discovered a mechanism that opens up new treatment strategies for tumors in which conventional chemotherapeutic ...
Feb 25, 2025
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A research team led by Prof. Jiang Yanyi from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has uncovered an important mechanism that enables squamous cell carcinoma (SCC) to resist ferroptosis, ...
Feb 19, 2025
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