University of Kentucky researchers have developed a new experimental model that could point the way toward more effective Alzheimer's disease treatments by targeting one of the brain's most important genes for risk and resilience.
Nov 17, 2025
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Free radicals generated at a specific site in non-neuronal brain cells called astrocytes may promote dementia, according to a Weill Cornell Medicine study. These findings, published in Nature Metabolism, demonstrated that ...
Nov 4, 2025
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Neurons have dominated neuroscience research for decades, but a growing body of evidence suggests that a group of non-neuronal brain cells called glia may play an equal or greater role in shaping brain health and disease. ...
Oct 23, 2025
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Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in ...
Oct 23, 2025
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New research suggests a missing brain molecule may hold the key to understanding—and potentially treating—the faulty neural circuits seen in Down syndrome. Restoring the molecule, called pleiotrophin, could enhance brain ...
Oct 17, 2025
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Women are affected by severe depression twice as often as men. The reasons for this have not yet been fully clarified. One potential factor is sex-specific differences in the blood-brain barrier. This barrier is formed by ...
Oct 16, 2025
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Why are we able to recall only some of our past experiences? A new study led by Jun Nagai at the RIKEN Center for Brain Science in Japan has an answer. Surprisingly, it turns out that the brain cells responsible for stabilizing ...
Oct 15, 2025
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A team of researchers at the University of Kentucky Sanders-Brown Center on Aging now have a better understanding of how the brain's support cells communicate with blood vessels—a process that goes awry in Alzheimer's disease.
Oct 9, 2025
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In lieu of animal experiments, researchers from the University of Rochester are using state-of-the-art microchips with human tissue to better understand how the brain operates under healthy conditions and is damaged through ...
Oct 7, 2025
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A study by Dorothy P. Schafer, Ph.D., and Travis E. Faust, Ph.D., at UMass Chan Medical School, explains how two different cell types in the brain—astrocytes and microglia—communicate in response to changes in sensory input ...
Oct 7, 2025
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