Three copies of chromosome 21 cause Down syndrome (DS), and roughly half of children born each year in the United States with DS—approximately 2,600—also have congenital heart defects (CHDs).
Oct 22, 2025
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New research suggests a missing brain molecule may hold the key to understanding—and potentially treating—the faulty neural circuits seen in Down syndrome. Restoring the molecule, called pleiotrophin, could enhance brain ...
Oct 17, 2025
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Down syndrome is associated with accelerated aging. It is estimated that up to 90% of individuals with the condition develop Alzheimer's disease before the age of 70. A study by researchers at the University of São Paulo ...
Oct 2, 2025
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When a sperm meets an egg, a lot has to go right for an embryo to develop into a complete organism. One critical step of early development is the reorganization of parental DNA to form a new unified genome, before the embryo ...
Sep 26, 2025
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In a new study published in Nature Communications, researchers from the Linda Crnic Institute for Down Syndrome (Crnic Institute) at the University of Colorado Anschutz discovered important differences in the physiological ...
Sep 25, 2025
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Adults with both Down syndrome and congenital heart defects, also known as congenital heart disease (CHD), are showing remarkable resilience despite facing significant medical challenges, according to a new MUSC study published ...
Sep 19, 2025
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Rett syndrome is a rare neurological condition that disrupts physical and linguistic development, affecting around one in 10,000 women and even fewer men. For decades, researchers assumed that people with the condition, many ...
Sep 3, 2025
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Women with Down syndrome have more advanced signs of Alzheimer's disease than men do at the average age of diagnosis, which is the same for both sexes, according to research by the University of California, Irvine. The findings, ...
Aug 12, 2025
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Sleep apnea, or difficulty breathing at night, is common among children with Down syndrome—affecting up to 80% compared to just 5% of the general pediatric population. Sleep apnea can negatively impact any child's ability ...
Aug 6, 2025
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Scientists at the USC Leonard Davis School of Gerontology have discovered a key connection between high levels of iron in the brain and increased cell damage in people who have both Down syndrome and Alzheimer's disease.
Jun 19, 2025
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