An update on the first clinical trial evaluating a pluripotent stem cell-derived neural stem cell therapy for Huntington's disease was presented at the ISSCR 2026 Annual Meeting. The Phase Ib/IIa REGEN4HD study represents ...
Jul 9, 2026
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A study conducted by the Sant Pau Research Institute (IR Sant Pau) and Hospital de Sant Pau has identified for the first time in living individuals a brain pattern related to the tau protein that changes according to the ...
Jul 6, 2026
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Huntington's disease is a devastating brain disorder in which decaying nerve cells lead to progressively worsening cognitive and movement abilities. While the genetic mutation responsible for the condition is well known, ...
Jul 1, 2026
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The hereditary disorder Huntington's disease has so far been considered incurable. Its clinical manifestations include impaired motor control and psychiatric symptoms. A new study offers promising insights. It shows that ...
Jun 29, 2026
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To function properly, neurons need to recycle cellular waste before it becomes toxic. When neurons can no longer do that, either due to aging or harmful genetic mutations, neurodegenerative disease can set in. One sign that ...
Jun 9, 2026
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Huntington disease is a rare, inherited brain disorder that progressively destroys nerve cells, leading to worsening movement, cognitive and psychiatric symptoms. Caused by a mutation in the huntingtin gene, the fatal disease ...
Jun 8, 2026
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Transposable elements (TEs), also called transposons, are DNA sequences capable of moving or replicating from one location to another within a genome. While TEs are the most significant fraction of the human genome (approximately ...
May 28, 2026
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Researchers have developed a technique that can identify errors caused by mutations linked to a range of genetic disorders, including forms of muscular dystrophy, Huntington's disease and amyotrophic lateral sclerosis (ALS), ...
May 21, 2026
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What if the very structures we thought were destroying the brain are actually trying to save it? A new study reveals that protein clumps, long considered toxic markers of diseases like Huntington's, act as a vital "quarantine" ...
May 19, 2026
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Treatments that target a fragment of the mutant protein that causes Huntington's disease might be more effective than treatments—now in clinical trials—that target the whole protein but leave this fragment intact, a new study ...
Mar 21, 2026
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