Scientists at La Trobe University have created a world-first method to investigate "disordered" proteins in living cells, in research that could change how we understand and treat Parkinson's disease.
Nov 26, 2024
0
27
The genetic mutation that causes Huntington's disease (HD)—a devastating brain disease that disrupts mobility and diminishes cognitive ability—may also enhance early brain development and play a role in promoting human intelligence.
Nov 13, 2024
0
45
Astrocytes—named for their star-like shape—are a type of brain cell as abundant as neurons in the central nervous system, but little is known about their role in brain health and disease.
Nov 6, 2024
0
16
Scientists at Northwestern and Case Western Reserve universities have developed the first polymer-based therapeutic for Huntington's disease, an incurable, debilitating illness that causes nerve cells to break down in the ...
Nov 1, 2024
0
57
Research led by scientists at Queen Mary University of London is signaling a new era for genetic sequencing and testing. In the largest study of its kind to date, published today in Nature Medicine, an international group ...
Oct 1, 2024
0
28
Researchers with McMaster University have discovered that the protein mutated in patients with Huntington disease doesn't repair DNA as intended, impacting the ability of brain cells to heal themselves.
Sep 27, 2024
0
67
For the first time, researchers have implicated the gene CHCHD2 in Huntington's disease (HD)—an incurable genetic neurodegenerative disorder—and identified the gene as a potentially new therapeutic target. In a brain organoid ...
Aug 22, 2024
0
47
In Huntington's disease, the mutant huntingtin gene (HTT) mRNA is retained in the nucleus and forms insoluble clusters. A new study shows that short interfering RNA (siRNA), an oligonucleotide therapeutic strategy that reduces ...
Jul 22, 2024
0
39
Research led by UCLA Health reveals that Black patients with Huntington's disease in the U.S. and Canada received their diagnoses, on average, one year later compared to white patients after symptoms first appear.
Jul 10, 2024
0
22
The genetic disease Huntington's not only affects nerve cells in the brain but also has widespread effects on microscopic blood vessels according to research.
Jun 9, 2024
0
57
