A novel quantitative PET- and MRI-based imaging approach can objectively identify a recently recognized type of dementia—limbic-predominant age-related TDP-43 encephalopathy, or LATE—that is often mistaken as Alzheimer's ...
Feb 26, 2026
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Jijing Wang, Ph.D., and Hyun-Sik Yang, MD, of the Department of Neurology at Mass General Brigham, are the lead and senior authors of a paper published in Molecular Neurodegeneration titled "Plasma TDP-43 is a potential biomarker ...
Nov 20, 2025
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Catholic nuns don't make a habit of participating in long-term studies on aging and dementia, but one notable exception has yielded critical insights into cognitive resilience, neuropathology and aging-related disorders.
Feb 26, 2025
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Researchers at the University of Kentucky's Sanders-Brown Center on Aging are at the forefront of advancing dementia research with groundbreaking work on a condition known as LATE, or "limbic predominant age-related TDP-43 ...
Jan 17, 2025
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In the ever-evolving field of Alzheimer's disease research, the development of disease-modifying therapies has sparked both excitement and debate. While these therapies represent a promising shift in the treatment landscape, ...
Sep 18, 2024
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A new type of degenerative brain disease, limbic-predominant age-related TDP-43 encephalopathy (LATE), was recognized just a decade or so ago, and remains relatively unknown.
Aug 13, 2024
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Limbic predominate age-related TDP-43 encephalopathy or LATE is a recently recognized form of dementia that affects memory, thinking and social skills. It mimics Alzheimer's disease or AD (and sometimes co-exists with it), ...
Dec 15, 2022
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