Cancer cells are quick to develop resistance to anti-tumor drugs. New research by scientists from the University of California, Davis, shows how cancers adapt to evade a class of anti-tumor drugs called BET inhibitors and ...
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For more than a decade, a class of drugs called BET inhibitors has been tested in cancer trials with high expectations. The biology looked promising. Many cancers depend on oncogenes that "Bromo- and Extra-Terminal domain" ...
Apr 9, 2026
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Cells behave like cities and organelles carry out infrastructural roles: mitochondria are powerhouses, the endoplasmic reticulum serves as a transport hub and lysosomes help with waste disposal. Communication between different ...
Mar 13, 2026
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It started with wine. Or more precisely, a conversation about it. "My colleagues and I were talking about how some people think drinking wine may be anti-inflammatory," recalls Xu Zhou, Ph.D., from the Division of Gastroenterology, ...
Nov 7, 2025
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More than 40 million people worldwide are living with HIV-1, which continues to be a major global health challenge due to its ability to persist silently within immune cells, evading complete eradication. Researchers at LKS ...
Jun 11, 2025
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Northwestern Medicine scientists have uncovered how a testis-specific protein contributes to tumor growth and progression in lung cancer, according to a study published in Science Advances.
Apr 24, 2025
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If you cut your arm or undergo surgery, scarring can be a good thing; the scar tissue produced by cells called fibroblasts helps you heal. In most organs of the body, however, the accumulation of scarring (called fibrosis) ...
Oct 23, 2024
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Hopes were high a decade ago, when a new class of drugs called BET inhibitors emerged for treating blood cancers and solid tumors. Since then, however, results from numerous clinical trials have painted a much more complex ...
Sep 10, 2024
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Using iPS cells generated from a patient with a myeloid neoplasm caused by a rare chromosomal rearrangement between the MECOM and MYC genes, a team of researchers led by Associate Professor Yoshinori Yoshida and Clinical ...
Sep 9, 2024
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A study used new molecular analyses to unravel the biological mechanisms of pediatric brain tumors and refine their classification. The research results were published in the journal Acta Neuropathologica Communications. ...
May 29, 2024
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