Younger adults with non-small cell lung cancer are significantly more likely than older patients to have genetic alterations that can be matched with targeted therapies, according to a large international study led in part ...
3 hours ago
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As the immune system battles cancer, chronic stimulation gradually drives T cells to a state of exhaustion. But some of these exhausted T cells can lose expression of the exhaustion marker LAG3, move out of the tumor and ...
Aug 18, 2026
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Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have identified a promising new strategy to overcome resistance to immunotherapy in colorectal cancer, one of the leading ...
May 7, 2026
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Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by using the patient's own T-cells to target tumors. However, they can cause rare, but potentially fatal cardiac inflammation known as ICI-myocarditis. ...
Jan 7, 2026
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Chronic liver inflammation is one of the most serious complications associated with liver cirrhosis. Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified a molecular mechanism that acts as ...
Dec 10, 2025
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A new study led by researchers at the Johns Hopkins Kimmel Cancer Center found that patients with advanced basal cell carcinoma (BCC) may benefit from receiving immunotherapy earlier in the course of treatment.
Nov 18, 2025
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Researchers at Moffitt Cancer Center have reported encouraging results from a phase 1B clinical trial showing that the immunotherapy drug avelumab, when combined with whole brain radiotherapy, may provide a safe and effective ...
Sep 30, 2025
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Northwestern Medicine scientists have discovered a new mechanism that controls a specialized group of T-cells, known as regulatory T-cells, and may serve as potential therapeutic targets to treat inflammatory disorders and ...
Oct 3, 2024
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Immune checkpoint inhibitors are a type of cancer treatment that helps the immune system attack cancer cells more effectively. One of the key proteins involved in this process is lymphocyte activation gene-3 (LAG3), which ...
Sep 4, 2024
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Scientists at deCODE genetics have published a study in Nature Communications, comparing over 110 thousand patients with autoimmune thyroid disease (AITD) from Iceland, Finland, UK and U.S. with 1.1 million controls. The ...
Jul 12, 2024
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