A new study led by NYU Langone Health researchers has found that cancer cells are better able to resist treatments when they have an abnormal number of chromosomes, the DNA strands wound up in bundles that control which genetic ...
May 7, 2026
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The cancer drugs called PARP inhibitors have a puzzling reputation: even though they are treatment mainstays for multiple forms of cancer, they can damage cancer-killing T cells and disrupt the potential for meaningful therapy. ...
Spinal cord damage—whether from traumatic injury or conditions such as spina bifida—can have a profound impact on bladder function. This can result in neurogenic bladder, a problem in which damage to the nerves involved in ...
Jul 30, 2025
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Excessive physical exercise, especially without adequate rest, can damage the human body in various ways. In severe cases, it can progress to overtraining syndrome, which is characterized by decreased performance and appetite, ...
Jul 2, 2025
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Mutations in BRCA2—a gene known to repair damaged DNA and suppress tumor formation—can predict an individual's predisposition to develop breast cancer, ovarian, prostate, pancreatic, and other epithelial tumors.
Mar 26, 2025
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Northwestern Medicine investigators have discovered new molecular mechanisms underlying DNA repair dysregulation in prostate cancer cells, findings that may inform the development of new targeted therapies for patients that ...
Dec 9, 2024
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According to a new study published in Nature Communications, researchers at the Department of Laboratory Medicine, Karolinska Institutet, have made a significant leap in drug discovery and development with a new method called ...
Dec 6, 2024
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Researchers at the Center for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within the nucleus, orchestrating ...
Nov 12, 2024
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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is incurable. The disease is characterized by the selective degeneration of upper motor neurons in the motor cortex as well as the lower motor neurons ...
Aug 22, 2024
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Lung cancer remains a leading global health concern, responsible for the highest number of cancer-related deaths worldwide. Central to its development is the tumor microenvironment, which involves a complex interplay with ...
May 15, 2024
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