Molecular Function: Notch Proteolysis and Signaling Pathway

Medical news and research articles

Drug can spur liver regeneration in Alagille syndrome

Research led by Associate Professor Duc Dong, Ph.D., has shown for the first time that the effects of Alagille syndrome, an incurable genetic disorder that affects the liver, could be reversed with a single drug. The study, ...

New insights into the mechanisms causing diabetes

Researchers led by Osaka University have now identified a mechanism by which a lack of insulin may be reported back to the pancreatic cells that produce insulin, identifying a potential new therapeutic target for diabetes.

Researchers develop novel platform to improve immunotherapy

Recent advances in immunotherapy for cancer have stimulated a plethora of studies aimed at developing T cells (white blood cells) and Natural Killer (NK) cells (immune cells with enzymes that can kill tumor cells or cells ...

Team discovers second stem cell type in mouse brain

In the brain of adult mammals, neural stem cells ensure that new nerve cells (neurons), are constantly formed. This process, known as adult neurogenesis, helps mice maintain their sense of smell. A research team led by Dr. ...

Genetic defects lead to enamel malformations

Mutations in a certain molecule result in severe damage in the structure and mineral composition of tooth enamel in mice, according to a study conducted at the UZH Center of Dental Medicine. The researchers combined genetic, ...

New role for blood-brain barrier in neuron function and damage

While the role of the blood-brain barrier has long been appreciated for its ability to maintain precise control over what molecules can enter the nervous system, very little is known about how the cells that form the barrier ...

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