Study in mice shows blocking abnormal stem cell signal during aging lessens related bone loss
A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.
Sep 27, 2023
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Molecular Function: Notch Proteolysis and Signaling Pathway
Medical news and research articles
International team identifies the mutations that cause the most frequent congenital heart defects
Bicuspid aortic valve is the most common congenital defect in humans, affecting between 1% and 2% of the population. Instead of the usual three symmetric leaflets, affected individuals have two asymmetric valve leaflets. ...
Jul 5, 2023
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Antibody treatment prevents intestinal graft versus host disease in preclinical tests
An experimental antibody treatment largely prevented a bone marrow transplant complication called graft versus host disease (GVHD) in the intestines, without causing broad immune suppression, in a preclinical study led by ...
Jun 28, 2023
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Scientists identify how some angiogenic drugs used to treat cancer and heart disease cause vascular disease
Research by scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has demonstrated that the on-target molecular and cellular effects of medicines used to modulate the formation of new blood vessels ...
May 31, 2023
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Putting radiation to the test to heal irregular heartbeat
Doctors are zapping the heart with radiation normally reserved for cancer, a bid to better treat people with life-threatening irregular heartbeats who've exhausted other options.
Apr 27, 2023
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Liver cells that intensify the progression of nonalcoholic fatty liver disease isolated
A team of medical scientists working at the University of Pennsylvania's Perelman School of Medicine has used single-nucleus RNA sequencing to isolate those mouse liver cells cells that push the progression of nonalcoholic ...
Drug can spur liver regeneration in Alagille syndrome
Research led by Associate Professor Duc Dong, Ph.D., has shown for the first time that the effects of Alagille syndrome, an incurable genetic disorder that affects the liver, could be reversed with a single drug. The study, ...
Jan 5, 2023
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New insights into the mechanisms causing diabetes
Researchers led by Osaka University have now identified a mechanism by which a lack of insulin may be reported back to the pancreatic cells that produce insulin, identifying a potential new therapeutic target for diabetes.
Nov 7, 2022
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Researchers develop novel platform to improve immunotherapy
Recent advances in immunotherapy for cancer have stimulated a plethora of studies aimed at developing T cells (white blood cells) and Natural Killer (NK) cells (immune cells with enzymes that can kill tumor cells or cells ...
Nov 3, 2022
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Team discovers second stem cell type in mouse brain
In the brain of adult mammals, neural stem cells ensure that new nerve cells (neurons), are constantly formed. This process, known as adult neurogenesis, helps mice maintain their sense of smell. A research team led by Dr. ...
Oct 5, 2022
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