A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL), the most common cancer in childhood and one that can be particularly difficult ...
May 20, 2025
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B-cell acute lymphoblastic leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common childhood cancer, making up 35% of pediatric cancer cases, but it can affect people of any ...
Mar 24, 2025
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Fourteen minutes ago, the nonprofit advocacy group Children's Cancer Cause posted on the social media app Twitter, now called X, that members were on Capitol Hill asking Congress for funding to fight #childhoodcancer.
Mar 18, 2025
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Manipulating the immune system to treat cancer has generated phenomenal responses in some patients, including complete cures, but those responses do not last for everyone. For example, chimeric antigen receptor (CAR) T–cell ...
Feb 25, 2025
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Just days before his fourth birthday, Santiago was diagnosed with B-cell acute lymphoblastic leukemia (B-ALL), the most common cancer in children. He began chemotherapy the next day, and the outlook was promising—disease-free ...
Dec 7, 2024
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Patients with relapsed or refractory CD19-positive B-cell acute lymphoblastic leukemia (ALL) who were treated with the novel anti-CD19 chimeric antigen receptor (CAR) T cell therapy, obecabtagene autoleucel (obe-cel), experienced ...
Nov 28, 2024
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The development of CAR-T technology in recent years has been a major milestone in the fight against cancer. These sort of "living drugs"—T-cells modified to expand, recognize and attack cancer cells within the body—offer ...
Oct 29, 2024
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More than 400 people, 80% of them being children under 14 years old, will be diagnosed with B-cell Acute Lymphoblastic Leukemia (B-ALL) next year in Spain, according to the latest projections from the Spanish network of cancer ...
Oct 21, 2024
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Researchers at Children's Hospital of Philadelphia (CHOP) revealed for the first time that children, adolescents and young adults may experience very rare neurological issues of paraparesis and quadriparesis following chimeric ...
Oct 8, 2024
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Clinical trial results from St. Jude Children's Research Hospital demonstrate the benefits of using genomics and early treatment response to guide risk classification of children with B-cell acute lymphoblastic leukemia (B-ALL).
Sep 24, 2024
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