Oral nucleoside antiviral is progressing toward future pandemic preparedness
Obeldesivir (GS-5245), a novel investigational small molecule oral antiviral, represents a new tool in the ongoing effort to prepare for future pandemics.
Jun 3, 2024
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Organic Chemical: remdesivir
Medical news and research articles
Study reports new compound that halts replication of COVID by targeting 'Mac-1' protein in cell models
Research appearing in the Journal of Medicinal Chemistry shows for the first time SARS-CoV-2, the virus responsible for COVID-19, can be inhibited from replicating in living cell cultures using a compound that targets "Mac-1," ...
Apr 25, 2024
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Significant global variation in COVID-19 guidelines: Most countries recommend at least one treatment that doesn't work
National clinical guidelines for the treatment of COVID-19 vary significantly around the world, with under-resourced countries the most likely to diverge from gold standard (World Health Organization; WHO) treatment recommendations, ...
Apr 22, 2024
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Researchers predict real-world SARS-CoV-2 evolution by monitoring mutations of viral isolates
Junior Associate Professor Kazuo Takayama (Department of Cell Growth and Differentiation) and a collaborative team of researchers in Japan recently characterized SARS-CoV-2 collected from a persistent COVID-19 patient to ...
Apr 3, 2024
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Risk profile tool provides clearer insight on hospitalized COVID-19 patients who benefit most from baricitinib treatment
A post-hoc analysis of ACTT-2 (Adaptive COVID-19 Treatment Trial-2) found that the use of a risk profile may more precisely characterize high-risk patients who may benefit from the use of baricitinib. The analysis is published ...
Feb 26, 2024
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Here's why some high-risk patients aren't getting drugs to combat COVID
As the toll from the COVID-19 pandemic continued to mount, antiviral medications such as Paxlovid were hailed by health officials as an important way to reduce the risk of severe illness or death.
Jan 25, 2024
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Two cases show COVID virus mutating around standard treatment remdesivir
Patients with weakened immune systems could be inadvertently helping COVID-19 develop resistance to the antiviral drug remdesivir, a new study reports.
Jan 23, 2024
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COVID-19 variant JN.1 is on the rise. Here's what you need to know
A new COVID-19 variant is now estimated to make up about 20% of COVID-19 cases in the United States.
Dec 21, 2023
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Q&A: Paxlovid to the rescue? What to know about the COVID-19 drug
As the holiday and peak respiratory seasons collide, and COVID-19 cases continue a steady, weeks-long climb, doctors want high-risk people to remember: Should COVID catch them in the coming days, one call to the doctor could ...
Dec 5, 2023
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WHO updates its guidance on treatments for COVID-19
A panel of international experts representing the World Health Organization's Guideline Development Group has updated its guidance on treatments for patients with COVID-19.
Nov 9, 2023
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