About a third of patients with diffuse large B cell lymphoma (DLBCL), a fast-growing form of lymphoma, will see their disease advance or recur following treatment. Seeking a new treatment strategy that might boost the effectiveness ...
Dec 10, 2024
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Researchers at the Icahn School of Medicine at Mount Sinai have discovered how genetics can affect the success of venetoclax, a treatment for multiple myeloma, a rare type of blood cancer. Their study, "Predictors of Response ...
Nov 29, 2024
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Researchers from Children's Hospital of Philadelphia (CHOP) have discovered the underlying biology that identifies a subset of patients with acute lymphoblastic leukemia who have a higher risk version of the disease and are ...
Nov 25, 2024
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Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer Research Center (DKFZ), ...
Nov 25, 2024
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Researchers from the Tumor Profiler consortium have combined single-cell multi-omics and functional profiling for 21 AML patients to reveal resistance mechanisms to the Bcl-2 inhibitor venetoclax and identify emerging treatment ...
Nov 11, 2024
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Ludwig Cancer Research scientists have devised new types of chimeric antigen-receptor (CAR) T cells—a type of cancer immunotherapy—that can be switched on to varying degrees of intensity and then switched off on demand with ...
Oct 22, 2024
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Northwestern Medicine investigators have discovered that a novel combination therapy promotes cancer cell death and tumor regression in mouse models of pancreatic cancer, according to a recent study published in the journal ...
Oct 10, 2024
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Scientists have discovered that a protein linked to prostate cancer is associated with more aggressive disease—it could be a new target for treatment and be used to help predict who will become resistant to hormone therapy.
Sep 18, 2024
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For researchers, projects can sometimes feel like babies, and there is nothing more satisfying than seeing your baby grow up. For William Tansey, professor of cell and developmental biology, this baby started 10 years ago ...
Sep 5, 2024
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Relapsed/refractory acute myeloid leukemia (AML), a blood cancer, has an extremely poor prognosis because of resistance to anti-cancer drugs and frailty of the patient's organ functions. A type of anti-tumor immunotherapy ...
Jul 18, 2024
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