Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have published a review on BH3 mimetics—a new class of drugs that are reshaping the treatment landscape for acute myeloid ...
Oct 23, 2025
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One huge reason why the world of medicine hasn't yet found "the cure" for hard-to-treat malignancies like acute myeloid leukemia (AML) and many other forms of cancer is that the world of science is still striving to fully ...
Oct 22, 2025
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Acute myeloid leukemia (AML), an aggressive and often fatal blood cancer, has long resisted a class of drugs called proteasome inhibitors, which work well in multiple myeloma.
Oct 20, 2025
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Researchers from Rutgers Health and other institutions have discovered why a powerful leukemia drug eventually fails in most patients—and found a potential way to overcome that resistance.
Oct 17, 2025
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Results of a recently published long-term follow-up of the ASAP trial, which was conducted at universities and clinics across Germany, show that the genetic risk of disease, not remission status, determines overall survival ...
Oct 6, 2025
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A research team at Lund University in Sweden has discovered a mechanism that helps acute myeloid leukemia cells to evade the body's immune system. By developing an antibody that blocks the mechanism, the researchers could ...
Oct 3, 2025
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As blood cancers are constantly evolving and developing mutations that grow resistance to current treatments, researchers in the University of Cincinnati Cancer Center's Leukemia and Drug Development Lab (LDDL) are constantly ...
Sep 15, 2025
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A gene called DNMT3A is important for guiding blood stem cells into forming all the cell types present in blood, including red blood cells, white blood cells and platelets. When this gene accumulates mutations—which might ...
Sep 11, 2025
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In the sport of sumo, a bout most commonly ends when one competitor is pushed or thrown outside of a ring of straw bales partially buried in clay. New research shows that using a drug as a blocker to outcompete the SUMO2 ...
Sep 4, 2025
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A Yale study published on the cover of the journal Blood explains basic scientific discoveries that could lead to innovative therapies for acute myeloid leukemia, and specifically a rare and aggressive blood cancer known ...
Sep 1, 2025
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