Immunology

Neuro-immune crosstalk in allergic asthma

Exactly how asthma begins and progresses remain a mystery, but a team led by researchers at Brigham and Women's Hospital and the Broad Institute of MIT and Harvard has uncovered a fundamental molecular cue that the nervous ...

Immunology

Scientists unearth cell 'checkpoint' that stops allergic diseases

Scientists from Trinity College Dublin have made a significant breakthrough in understanding the regulation of immune cells that play a pivotal role in allergic diseases such as asthma and eczema. They have identified a 'checkpoint' ...

Neuroscience

Targeting nerve endings to curb allergic asthma

Current asthma medications, which work by suppressing inflammatory signaling by immune cells or by dilating the airways, can stop working over time. A study from Boston Children's Hospital, Brigham and Women's Hospital, and ...

Medical research

Novel mechanism of action of corticosteroids in allergic diseases

Research by Peter Barnes (Imperial College, London) and colleagues may explain the effectiveness of common treatments for allergic inflammation and may point the way to targets for new treatments for allergic diseases, according ...

Immunology

Pathway to resolve allergic asthma is discovered

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a certain protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible ...

Genetics

Study uncovers gene's contribution to asthma susceptibility

New research from the University of Minnesota College of Veterinary Medicine (CVM) has uncovered the role gene ORMDL3 plays in the disease asthma. ORMDL3, a gene recently linked to asthma susceptibility, has now been linked ...

Immunology

Allergic asthma: Researchers identify a key molecule

Allergies are becoming more commonplace, particularly in industrialised coun-tries. In addition to hay fever, allergic asthma is currently considered to be one of the most widespread allergies. UFZ researchers and their colleagues ...

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