Emergency anaphylaxis observation times can be cut for children

Most children seen in the emergency department for anaphylaxis can be discharged after two hours or less, according to a study presented at the annual meeting of the Pediatric Academic Societies, held from April 27 to May ...


Emergency room anaphylaxis observation times could be reduced

According to a new national study, most children visiting hospital emergency departments with anaphylaxis, a severe and potentially life-threatening allergic reaction, could be discharged after two hours or less—which is ...

Diseases, Conditions, Syndromes

Some 'anaphylactic' reactions to flu shots may just be stress responses

Some adverse reactions to influenza vaccinations may be safe to de-labeled—that is, deemed safe for further flu vaccinations—from "allergies" to "stress-related responses" because they do not meet the criteria for anaphylaxis, ...

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Anaphylaxis is defined as "a serious allergic reaction that is rapid in onset and may cause death". It typically results in a number of symptoms including an itchy rash, throat swelling, and low blood pressure. Common causes include insect bites, foods, and medications.

On a pathophysiologic level, anaphylaxis is due to the release of mediators from certain types of white blood cells triggered either by immunologic or non-immunologic mechanisms. It is diagnosed based on the presenting symptoms and signs. The primary treatment is injection of epinephrine, with other measures being complementary.

Worldwide 0.05–2% of people are estimated to have anaphylaxis at some point in their life and rates appear to be increasing. The term comes from the Greek words ἀνά ana, against, and φύλαξις phylaxis, protection.

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