Investigators were able to halt the growth of glioblastoma, an aggressive form of brain cancer, by inhibiting an enzyme called CDK5, according to a Northwestern Medicine study published in Cell Reports.
May 11, 2018
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Glioblastoma—a universally fatal form of brain cancer—is known for its ability to hijack immune checkpoints and evade detection and destruction by the body's immune defenses. But many of the details underlying this feat ...
Mar 7, 2018
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An international team of researchers has genetically engineered cancer-killing immune cells that can hunt brain tumors displaying a new molecular target that is highly prevalent on brain cancer cells. Based on the findings ...
Feb 28, 2018
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Zika virus, known for causing microcephaly in babies by attacking the cells that give rise to the fetus's cerebral cortex, could be an alternative for treatment of glioblastoma, the most common and aggressive malignant brain ...
Feb 22, 2018
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Glioblastoma multiforme is one of the most common and deadly brain tumors. Despite the initial responsiveness to state-of-the-art therapies, tumors virtually always become resistant and eventually recur. Researchers at Dartmouth's ...
Feb 16, 2018
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When Leland Dunwoodie, an undergraduate researcher in biochemistry, approached his PI about wanting to start research on "some human stuff" in the spring of 2016, he didn't imagine it would lead to the discovery of 22 genes ...
Feb 8, 2018
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(HealthDay)—For patients with glioblastoma, the addition of tumor-treating fields (TTFields) to standard treatment with temozolomide is associated with improved survival without negative effects on health-related quality ...
Feb 4, 2018
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A Virginia Tech Carilion Research Institute team has identified a new therapeutic target to treat glioblastoma, the most devastating and common form of brain cancer.
Jan 31, 2018
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In animal experiments, a human-derived glioblastoma significantly regressed when treated with the combination of an experimental enzyme inhibitor and the standard glioblastoma chemotherapy drug, temozolomide.
Jan 23, 2018
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A diagnosis of the brain cancer glioblastoma carries a dismal prognosis, with most patients dying within five years. Now a team led by Massachusetts General Hospital (MGH) investigators has found that adding the chemotherapy ...
Jan 22, 2018
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