Oncology & Cancer
Anti-anxiety drug may improve brain cancer survival chances
A new study shows that cerebrospinal fluid reduces current treatment efficacy in brain cancer and identifies new therapeutic opportunities.
Oct 25, 2023
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116
Glioblastoma
Oncology & Cancer
Editorial: GBP3-STING interaction in glioblastoma coordinates poor response to temozolomide
A new editorial paper was published in Oncotarget, titled "GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative, and DNA repair programs in response to temozolomide."
Oct 17, 2023
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0
Oncology & Cancer
Study shows mitochondrial protein plays key role in glioblastoma and therapeutic resistance
Glioblastoma is the most common type of brain tumor that affects adults and, unfortunately, still remains incurable. In a new study, researchers have demonstrated that a specific mitochondrial protein plays an important role ...
Oct 17, 2023
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Oncology & Cancer
Zebrafish avatars can help tailor glioblastoma therapies
Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study published in EMBO Molecular Medicine.
Oct 4, 2023
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30
Oncology & Cancer
Gene linked to glioblastoma stem cell self-renewal and immunosuppression
Northwestern Medicine scientists have identified how one gene connects glioblastoma stem cell self-renewal to microglia immunosuppression in glioblastoma, according to a new study published in Nature Immunology.
Sep 27, 2023
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36
Medications
Combination immunotherapy shows no additional benefit for most advanced cancers, finds meta-analysis
A combination immunotherapy treatment of nivolumab plus ipilimumab was associated with no improvement in survival for advanced cancers other than melanoma, when compared to nivolumab alone, according to a recent Northwestern ...
Sep 22, 2023
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59
Medical research
Research team leads adaptive, efficient multi-arm phase 2 clinical trial for glioblastoma
An innovative phase 2 clinical trial led by Dana-Farber Cancer Institute, in collaboration with 10 major brain tumor centers around the country and designed to find new potential treatments for glioblastoma, has reported ...
Sep 18, 2023
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0
Oncology & Cancer
Brain cancer linked to nuclear pore alterations
Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs). These structures are embedded in the nuclear envelope, a membrane barrier that separates ...
Sep 15, 2023
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50
Medical research
Discovery of protein-protein interaction lays foundation for future glioblastoma therapy
The discovery of a previously unknown molecular target has inspired what may become a therapeutic breakthrough for people with glioblastoma, the most common and aggressive brain cancer.
Sep 11, 2023
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92
Oncology & Cancer
Study could help explain why certain brain tumors don't respond well to immunotherapy
A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center sheds new light on why tumors that have spread to the brain from other parts of the body respond to immunotherapy while glioblastoma, an aggressive ...
Sep 1, 2023
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