Chugai Pharmaceutical announced today that the preclinical study findings on its original bispecific antibody ERY974, a molecule that binds Glypican-3 and CD3 simultaneously, and that is currently under development as a Phase ...
Oct 5, 2017
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Lactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis and autoimmune diseases, which is known as the Warburg effect. Despite being an important metabolic ...
Jan 4, 2023
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(HealthDay)—Late recurrence after hepatocellular carcinoma (HCC) resection is associated with sex, cirrhosis, and several aggressive tumor characteristics of the initial HCC, according to a study recently published in JAMA ...
Dec 14, 2018
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Professor Wenbiao Hu from the QUT School of Public Health and Social Work said the team had looked at the possible influence of environmental changes given that liver cancer had increased in the face of decreases in known ...
Jan 19, 2023
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Hepatocellular carcinoma (HCC) is one of the few cancers in which a continued increase in incidence has been observed over recent years. Globally, there are approximately 750,000 new cases of liver cancer reported each year. ...
Dec 3, 2014
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A study led by Xiujun Cai (Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine) screened the whole genome of hepatocellular carcinoma cells (HepG2) through CRISPR / cas9 system ...
Apr 19, 2022
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(HealthDay)—Insulin resistance assessed by homeostasis model assessment index (HOMA2-IR) correlates with the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus (HBV) infection, according to ...
Nov 19, 2016
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Diabetes was associated with an increased risk for developing a type of liver cancer called hepatocellular carcinoma, and this association was highest for Latinos, followed by Hawaiians, African-Americans, and Japanese-Americans, ...
Dec 8, 2013
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A study, published in the journal Gene Expression and led by Brady Jin-Smith from the Department of Pathology at Tulane University, focuses on ALDHs, a group of key enzymes that catalyze the irreversible oxidation of various ...
Dec 15, 2023
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Hepatocellular carcinoma (HCC) is a common human disease and one of the main causes of cancer-related death. The angiogenesis inhibitor Sorafenib (SORA) is commonly used in the treatment of advanced HCC as a first-line drug.
Feb 7, 2024
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