Diseases, Conditions, Syndromes

Cascade of events leading to prion disease described

Prion diseases are deadly neurodegenerative disorders in humans and animals that are characterized by misfolded forms of prion protein (PrP). Development of effective treatments has been hampered by the lack of good experimental ...

Diseases, Conditions, Syndromes

France reports lone case of mad cow disease

France has confirmed an isolated case of mad cow disease in a five-year-old cow that died in the northeast Ardennes region.

Surgery

Innovation in neurosurgery

As medical students, we don't get much intra-curricular exposure to surgery. Then there is the neurophobia, a chronic condition whose main symptom is the inability to apply knowledge of neuroscience to clinical situations. ...

Alzheimer's disease & dementia

Injections may have passed on Alzheimer's 'seeds': study

People injected with hormones extracted from cadaver brains in a long-abandoned procedure may have received "seeds" of Alzheimer's disease, said a study Wednesday, urging research into possible risks for "accidental" medical ...

Medical research

Finding a way forward in the fight against prion disease

For much of her adult life Valerie Sim has been fascinated by a disease very few in the world can claim to even begin to understand. Sim is one of Canada's foremost authorities on prion disease—more commonly known as bovine ...

Medical research

New drug offers hope in fight against mad cow disease

A new drug compound could lead to a breakthrough in the fight against bovine spongiform encephalopathy, the incurable brain-wasting disease also known as mad cow disease, researchers said Wednesday.

Medical research

Prion protein protects against epilepsy

In the most systematic and rigorous study conducted thus far in its field, the prion protein (PrPC) was clearly shown to play a role in preventing the onset of epileptic seizures. PrPC is perhaps best known in its 'degenerate' ...

Diseases, Conditions, Syndromes

Australian gets fatal 'one-in-a-million' brain disease

An Australian has been diagnosed with a deadly "one-in-a-million" degenerative brain condition, but authorities Wednesday stressed it was unrelated to mad cow disease and not contagious.

Neuroscience

Long-term memories are maintained by prion-like proteins

Research from Eric Kandel's lab at Columbia University Medical Center (CUMC) has uncovered further evidence of a system in the brain that persistently maintains memories for long periods of time. And paradoxically, it works ...

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