Medical research

Gene therapy in mice builds muscle, reduces fat

Exercise and physical therapy often are recommended to help people who have arthritis. Both can strengthen muscle—a benefit that also can reduce joint pain. But building muscle mass and strength can take many months and ...

Medical research

Substituting the next-best protein

When an actor is unable to perform in the theatre, an understudy—ideally one with some practice in the role—can take her place on stage. A study from Dr. Bernard Jasmin's laboratory at the University of Ottawa and published ...

Medical research

Cancer cachexia: Extracellular ligand helps to prevent muscle loss

Cancer cachexia is a complex metabolic disease accounting for approximately one third of all cancer-related deaths worldwide. So far, there is no effective therapy for this muscle wasting disease. Researchers from the Leibniz ...

Genetics

New gene correction therapy for Duchenne muscular dystrophy

Duchenne type muscular dystrophy (DMD) is the most common hereditary muscular disease among children, leaving them wheelchair-bound before the age of 12 and reducing life expectancy. Researchers at Technical University of ...

Medical research

New treatment for muscular dystrophy wins US regulatory approval

Research led by Professor Steve Wilton and Professor Sue Fletcher and licensed to Sarepta Therapeutics has delivered a second treatment for Duchenne muscular dystrophy, with the drug gaining accelerated approval by the U.S. ...

Medications

Spironolactone noninferior in Duchenne muscular dystrophy

(HealthDay)—In a head-to-head study of mineralocorticoid receptor antagonists, spironolactone was found to be noninferior to eplerenone for slowing the progression of heart damage in boys with Duchenne muscular dystrophy ...

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