For the first time, researchers have mapped the genomes of tapeworms to reveal potential drug targets on which existing drugs could act. The genomes provide a new resource that offers faster ways to develop urgently needed ...
Mar 13, 2013
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The World Health Organization on Thursday urged countries to invest billions of dollars to tackle 17 neglected tropical diseases—including dengue fever, leprosy and sleeping sickness—which kill 500,000 people globally ...
Feb 19, 2015
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A protein known for helping cells withstand stress may also act as a switch that triggers free-swimming Schistosoma larvae to begin penetrating the skin and transforming into the parasitic flatworms that burden more than ...
Sep 9, 2016
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A chance encounter in northern Australia with a previously undocumented parasite has allowed scientists to join important evolutionary dots, highlighting the need for closer monitoring of exotic and neglected tropical diseases.
Jan 13, 2017
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Identifying dengue fever "hot spots" can provide a predictive map for outbreaks of chikungunya and Zika—two other viral diseases that, along with dengue, are spread by the Aedes aegypti mosquito.
May 11, 2018
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A relatively inexpensive program set up to combat river blindness, an infectious disease, has resulted in major health improvements in Africa, shows a study conducted by Erasmus University Medical Center researchers. The ...
Jan 31, 2013
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Water-associated infectious disease outbreaks are more likely to occur in areas where a region's population density is growing, according to a new global analysis of economic and environmental conditions that influence the ...
Feb 14, 2012
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(Medical Xpress)—Stealth is a well-known concept in military tactics. Almost since the invention of radar, the hunt began for counter-technologies to hide aircraft and missiles from detection – most successfully by modifying ...
Feb 5, 2013
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Genetic variants in a region of the genome linked to our immune response have been linked to increased risk of podoconiosis, a disfiguring and disabling leg swelling caused by an abnormal reaction to the minerals found in ...
Mar 28, 2012
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(Medical Xpress)—Stopping the spread of dengue infection— a potentially fatal tropical disease transmitted by the Aedes aegypti mosquito— could be one of the biggest challenges of our time. About half of the human ...
Mar 21, 2013
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The neglected diseases are a group of tropical infections which are especially endemic in low-income populations in developing regions of Africa, Asia, and the Americas. Different organizations define the set of diseases differently. In sub-Saharan Africa, the impact of these diseases as a group is comparable to malaria and tuberculosis. Some of these diseases have known preventive measures or acute medical treatments which are available in the developed world but which are not universally available in poorer areas. In some cases, the treatments are relatively inexpensive. For example, the treatment for schistosomiasis is USD $0.20 per child per year. Nevertheless, control of neglected diseases[clarification needed] is estimated to require funding of between US$2 billion to US$3 billion over the next five to seven years.
These diseases are contrasted with the big three diseases (HIV/AIDS, tuberculosis, and malaria), which generally receive greater treatment and research funding. The neglected diseases can also make HIV/AIDS and tuberculosis more deadly. However, some pharmaceutical companies have committed to donating all the drug therapies required and mass drug administration has been successfully accomplished in several countries.
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