Neuroscience

Researchers unlock new mechanism in pain management

It's in the brain where we perceive the unpleasant sensations of pain, and researchers have long been examining how calcium channels in the brain and peripheral nervous system contribute to the development of chronic pain ...

Medical research

Putting a number on pain

"How much pain are you in?" It's a harder question than many people think. Tools for assessing patients' pain—be they children or adults—rely on perception: a subjective measure that eludes quantification and can change ...

Oncology & Cancer

New combination drug controls tumor growth and metastasis in mice

Researchers at UC Davis, University of Massachusetts and Harvard Medical School have created a combination drug that controls both tumor growth and metastasis. By combining a COX-2 inhibitor, similar to Celebrex, and an epoxide ...

Medical research

One molecule to block both pain and itch

Duke University researchers have found an antibody that simultaneously blocks the sensations of pain and itching in studies with mice.

Neuroscience

Researchers find new target for chronic pain treatment

Researchers at the UNC School of Medicine have found a new target for treating chronic pain: an enzyme called PIP5K1C. In a paper published today in the journal Neuron, a team of researchers led by Mark Zylka, PhD, Associate ...

Medical research

How cone snail venom minimizes pain

The venom from marine cone snails, used to immobilize prey, contains numerous peptides called conotoxins, some of which can act as painkillers in mammals. A recent study in The Journal of General Physiology provides new insight ...

Neuroscience

Study identifies new drug target for chronic, touch-evoked pain

(Medical Xpress)—Researchers at the School of Medicine have identified a subset of nerve cells that mediates a form of chronic, touch-evoked pain called tactile allodynia, a condition that is resistant to conventional pain ...

Medical research

Possible safe and novel painkillers from tarantula venom

(Medical Xpress)—Screening more than 100 spider toxins, Yale researchers identified a protein from the venom of the Peruvian green velvet tarantula that blunts activity in pain-transmitting neurons. The findings, reported ...

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