Medications

FDA reports Samsca may cause liver damage

(HealthDay)—After reviewing data from recent large clinical trials, the U.S. Food and Drug Administration has determined that Samsca (tolvaptan) should not be used for longer than 30 days and should not be used at all by ...

Genetics

Gene mutation leads to poorly understood birth defects

Scientists have identified genetic mutations that appear to be a key culprit behind a suite of birth defects called ciliopathies, which affect an estimated 1 in 1,000 births. In a paper published online this week in Nature ...

Diseases, Conditions, Syndromes

Researchers develop potential treatment for fatal kidney disease

Researchers at UT Southwestern Medical Center, working with a California biotech firm, have developed a potential drug to treat polycystic kidney disease - an incurable genetic disease that often leads to end-stage kidney ...

Pediatrics

New study paints grim health picture for obese teens

(HealthDay)—Severely obese teens are at increased risk for a host of serious health problems as adults, including asthma, kidney disease and sleep disorders, according to a new study.

Genetics

Revealed: The biochemical pathways of kidney disease

According to PKD International, 12.5 million people are affected by polycystic kidney disease. There is no known cure. But that may one day change, thanks in part to new research by a Concordia biology researcher.

Genetics

New technique provides novel approach to diagnosing ciliopathies

Cilia, the cell's tails and antennas, are among the most important biological structures. They line our windpipe and sweep away all the junk we inhale; they help us see, smell and reproduce. When a mutation disrupts the function ...

Surgery

'World-first' surgery gives Australian boy new hope

Australian doctors Thursday hailed what they described as a world-first surgical treatment for a boy suffering from a rare disease that sends his blood pressure soaring and triggered a stroke.

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