Drugs that selectively kill senescent cells may benefit otherwise healthy older women but are not a "one-size-fits-all" remedy, Mayo Clinic researchers have found. Specifically, these drugs may only benefit people with a ...
Jul 2, 2024
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Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease marked by the thickening and scarring of lung tissue with unclear etiology. Affecting around five million people worldwide, IPF causes severe respiratory ...
Jun 12, 2024
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Patients with pulmonary fibrosis from the poorest areas had more severe symptoms by the time they saw a hospital doctor and had a poorer survival rate than those living in wealthier areas, according to the new research.
May 9, 2024
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Researchers at Boston Medical Center (BMC) and Boston University (BU) have published a new study detailing the development of a method for generating human alveolar epithelial type I cells (AT1s) from pluripotent stem cells ...
Apr 22, 2024
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Scientists have long known that white blood cells called macrophages accumulate in the lungs of people suffering from pulmonary fibrosis. What role macrophages play in developing the often fatal lung disease is less clear.
Apr 12, 2024
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Pulmonary diseases are a leading cause of morbidity and mortality worldwide. For many progressive lung diseases like idiopathic pulmonary fibrosis (IPF), a key issue is a low supply of new stem cells to repair and reverse ...
Apr 10, 2024
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Regulators of gene expression are thought to play an outsized role in disorders from cancers to heart disease. But how exactly do variations in gene regulation translate into a disease's biology?
Mar 28, 2024
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Researchers at Weill Cornell Medicine have discovered a protein called SEL1L that plays a critical role in clearing collagen from tissue, and that may be a therapeutic target to help prevent fibrosis, scar tissue that interferes ...
Mar 26, 2024
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UVA Health researchers have discovered a potential way to predict which patients with severe COVID-19 are likely to recover well and which are likely to suffer "long-haul" lung problems. That finding could help doctors better ...
Mar 15, 2024
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A RIKEN-developed mouse model of an enigmatic lung disease promises to unlock new biological insights and catalyze the development of treatments for millions affected globally. The research is published in Nature Communications.
Mar 5, 2024
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