Health

The wellness boost of a purposeful life

(HealthDay)—Research has long shown how psychological disorders lead to poor physical health. Now scientists are learning more about the flip side of emotions, how living a purposeful life may have as many physical benefits ...

Neuroscience

Increased corticomotor excitability ID'd in restless legs

(HealthDay)—For patients with restless leg syndrome (RLS), the primary motor cortex (M1) exhibits hyperexcitability, which is associated with disease severity, according to a study published recently in Sleep Medicine.

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Restless legs syndrome (RLS) or Willis-Ekbom disease is a neurological disorder characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations. It most commonly affects the legs, but can affect the arms, torso, and even phantom limbs. Moving the affected body part modulates the sensations, providing temporary relief.

RLS sensations can most closely be compared to an itching or tickling in the muscles, like "an itch you can't scratch" or an unpleasant "tickle that won't stop." The sensations typically begin or intensify during quiet wakefulness, such as when relaxing, reading, studying, or trying to sleep. In addition, most individuals with RLS have limb jerking during sleep, which is an objective physiologic marker of the disorder and is associated with sleep disruption. Some controversy surrounds the marketing of drug treatments for RLS. It is a "spectrum" disease with some people experiencing only a minor annoyance and others experiencing major disruption of sleep and significant impairments in quality of life.

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