Restless Legs Syndrome

Sensory stimuli control dopamine in the brain

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A new gene identified for restless legs syndrome

People suffering from restless legs syndrome (RLS) experience unpleasant sensations in the legs at night for which the only remedy is movement. Now, an international consortium from Europe, Canada and the US has identified ...

Jul 14, 2011
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Restless legs syndrome (RLS) or Willis-Ekbom disease is a neurological disorder characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations. It most commonly affects the legs, but can affect the arms, torso, and even phantom limbs. Moving the affected body part modulates the sensations, providing temporary relief.

RLS sensations can most closely be compared to an itching or tickling in the muscles, like "an itch you can't scratch" or an unpleasant "tickle that won't stop." The sensations typically begin or intensify during quiet wakefulness, such as when relaxing, reading, studying, or trying to sleep. In addition, most individuals with RLS have limb jerking during sleep, which is an objective physiologic marker of the disorder and is associated with sleep disruption. Some controversy surrounds the marketing of drug treatments for RLS. It is a "spectrum" disease with some people experiencing only a minor annoyance and others experiencing major disruption of sleep and significant impairments in quality of life.

This text uses material from Wikipedia licensed under CC BY-SA

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