An international research team led by investigators from Massachusetts General Hospital (MGH) and the University of Exeter Medical School has identified 57 gene regions associated with symptoms of insomnia. Their report, ...
Feb 25, 2019
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A new study into the genetics underlying restless legs syndrome has identified 13 previously-unknown genetic risk variants, while helping inform potential new treatment options for the condition.
Oct 13, 2017
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An international team of researchers has found, for the first time, seven risk genes for insomnia. With this finding the researchers have taken an important step towards the unravelling of the biological mechanisms that cause ...
Jun 12, 2017
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A team of American and British scientists have for the first time discovered genetic connections between sleep disturbance and a range of medical disorders including obesity.
Dec 19, 2016
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Johns Hopkins researchers believe they may have discovered an explanation for the sleepless nights associated with restless legs syndrome (RLS), a symptom that persists even when the disruptive, overwhelming nocturnal urge ...
May 7, 2013
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When flies are made to lose a gene with links to Restless Legs Syndrome (RLS), they suffer the same sleep disturbances and restlessness that human patients do. The findings reported online on May 31 in Current Biology strongly ...
May 31, 2012
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About one in three adults in the United States report routinely not getting enough sleep. Sleep insufficiency is associated with increased risk for diabetes, cardiovascular disease, mental health problems, injuries, loss ...
Jan 11, 2023
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Restless leg syndrome (RLS) is more common in psoriasis patients and is associated with more severe psoriasis, according to a study published online Dec. 5 in the International Journal of Dermatology.
Dec 15, 2022
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If you're thinking about getting a device to help you sleep better, an expert offers some advice.
Apr 11, 2022
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DEAR MAYO CLINIC: My child moves around a lot at bedtime and has trouble falling asleep. She describes "bugs" on her legs. As someone who was diagnosed with restless legs syndrome, I am wondering if children can develop restless ...
Jan 28, 2022
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Restless legs syndrome (RLS) or Willis-Ekbom disease is a neurological disorder characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations. It most commonly affects the legs, but can affect the arms, torso, and even phantom limbs. Moving the affected body part modulates the sensations, providing temporary relief.
RLS sensations can most closely be compared to an itching or tickling in the muscles, like "an itch you can't scratch" or an unpleasant "tickle that won't stop." The sensations typically begin or intensify during quiet wakefulness, such as when relaxing, reading, studying, or trying to sleep. In addition, most individuals with RLS have limb jerking during sleep, which is an objective physiologic marker of the disorder and is associated with sleep disruption. Some controversy surrounds the marketing of drug treatments for RLS. It is a "spectrum" disease with some people experiencing only a minor annoyance and others experiencing major disruption of sleep and significant impairments in quality of life.
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