Medical research

Sunlight continues to damage skin in the dark

Much of the damage that ultraviolet radiation (UV) does to skin occurs hours after sun exposure, a team of Yale-led researchers concluded in a study that was published online Feb. 19 by the journal Science.

Medical research

Scientists discover master regulator of skin development

The surface of your skin, called the epidermis, is a complex mixture of many different cell types—each with a very specific job. The production, or differentiation, of such a sophisticated tissue requires an immense amount ...

Diseases, Conditions, Syndromes

Mosquito-borne diseases could be prevented by skin cream

A skin cream used to treat warts and skin cancer could help protect people against viral diseases such as Zika and dengue, according to new research from the University of Leeds.

Oncology & Cancer

Immune response against skin-dwelling viruses prevents cancer

Viruses get a bad rap as potential cancer-causers, but at least one class of viruses that commonly live on human skin—so-called "low-risk" human papillomaviruses—appear to play an unwitting role in protecting us against ...

Oncology & Cancer

Inactive receptor renders cancer immunotherapies ineffective

The aim of immunotherapies is to enable the immune system to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose. However, they are only effective in about one-third ...

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Skin neoplasms (also known as "skin cancer") are skin growths with differing causes and varying degrees of malignancy. The three most common malignant skin cancers are basal cell cancer, squamous cell cancer, and melanoma, each of which is named after the type of skin cell from which it arises. Skin cancer generally develops in the epidermis (the outermost layer of skin), so a tumor can usually be seen. This means that it is often possible to detect skin cancers at an early stage. Unlike many other cancers, including those originating in the lung, pancreas, and stomach, only a small minority of those affected will actually die of the disease, though it can be disfiguring. Melanoma survival rates are poorer than for non-melanoma skin cancer, although when melanoma is diagnosed at an early stage, treatment is easier and more people survive.

Skin cancer is the most commonly diagnosed type of cancer. Melanoma and non-melanoma skin cancers combined are more common than lung, breast, colorectal, and prostate cancer. Melanoma is less common than both basal cell carcinoma and squamous cell carcinoma, but it is the most serious — for example, in the UK there were over 11,700 new cases of melanoma in 2008, and over 2,000 deaths. It is the second most common cancer in young adults aged 15–34 in the UK. Most cases are caused by over-exposure to UV rays from the sun or sunbeds. Non-melanoma skin cancers are the most common skin cancers. The majority of these are basal cell carcinomas. These are usually localized growths caused by excessive cumulative exposure to the sun and do not tend to spread.

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