Arthritis & Rheumatism

Researchers reveal how receptor TLR-9 protects against lupus

When the pathogen-sensing intracellular receptors TLR-7 and TLR-9 were implicated in systemic lupus erythematosus (SLE), it was suspected that their removal would lessen the severity of the disease. However, while this held ...

Immunology

Clues to lupus's autoimmune origins in precursor cells

In the autoimmune disease systemic lupus erythematosus or SLE, the immune system produces antibodies against parts of the body itself. How cells that produce those antibodies escape the normal "checks and balances" has been ...

Arthritis & Rheumatism

Clinical advances in systemic lupus erythematosus

The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate exciting advances for individuals suffering from systemic lupus erythematosus (SLE). The first is a phase ...

Immunology

Sirtuin-1 levels linked to lupus

The Cardiometabolic and Kidney Risk Research Group, in collaboration with the Genomic and Genetic Diagnosis Unit of the Health Research Institute of Valencia's Hospital Clínico, INCLIVA, the Department of Biochemistry and ...

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