Immunology

How chronic infections can outsmart the immune system

Professor Simona Stäger and her team at INRS have discovered a mechanism that causes the body to sabotage its own defenses against infection by visceral leishmaniasis, a fatal tropical disease. This discovery could help ...

Diseases, Conditions, Syndromes

Discovery of a new potential treatment for visceral leishmaniasis

A new preclinical candidate drug with the potential to treat visceral leishmaniasis, one of the world's major neglected diseases, has been discovered through a close collaboration between the University of Dundee, GSK and ...

Diseases, Conditions, Syndromes

New information on a major player in chronic visceral leishmaniasis

In an article in the latest issue of PLOS Pathogens, INRS professor Simona Stäger and her team show how the parasite Leishmania donovani uses a physiological response to low oxygen levels (hypoxia) to establish a chronic ...

Diseases, Conditions, Syndromes

Skin plays significant role in spread of leishmaniasis

Scientists at the University of York have discovered that parasites responsible for leishmaniasis - a globally occurring neglected tropical disease spread by sand flies - are mainly acquired from the skin rather than a person's ...

Diseases, Conditions, Syndromes

Leishmaniasis infection on the rise in US ecotourists, soldiers

Driven by burgeoning ecotourism and military campaigns in Iraq and Afghanistan, a parasitic infection called leishmaniasis is showing up in more U.S. patients, often stumping doctors. Rapid diagnostic tests and innovative ...

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