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Study identifies potential novel drug to treat tuberculosis
A new study published in Microbiology Spectrum demonstrates that a novel semi-synthetic compound can be derived from natural compounds to produce potent activity against Mycobacterium tuberculosis, including multi-drug resistant ...
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Diseases, Conditions, Syndromes
Endolymphatic hydrops tied to hearing loss severity in Meniere disease
For patients with bilateral Meniere disease (MD), features of endolymphatic hydrops correlate with the severity of hearing loss and staging of MD, according to a study published online Sept. 16 in Head & Face Medicine.
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Lyme disease and ticks that carry it spread across the US
Lyme disease is one of the most prevalent insect-borne diseases in the country, with far more cases each year than other diseases carried by mosquitoes, fleas and ticks, such as the West Nile virus.
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New genomic surveillance tools could help efforts to eliminate damaging parasitic infections
Researchers at Washington University School of Medicine in St. Louis have developed a new genomic-based approach that could aid global efforts to eliminate lymphatic filariasis, a parasitic roundworm infection spread by mosquitos. ...
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Synthetic peptide acts as molecular shield to prevent SARS-CoV-2 from infecting cells
A peptide synthesized by researchers at the University of São Paulo (USP) in Brazil protected human lung cells against infection by SARS-CoV-2 in the laboratory and eliminated the inflammation caused by the virus in mice ...
18 hours ago
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Viruses found hiding in lungs' immune cells long after initial illness
Doctors have long known that children who become seriously ill with certain respiratory viruses such as respiratory syncytial virus (RSV) are at elevated risk of developing asthma later in life. What they haven't known is ...
20 hours ago
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Organ allocation changes lead to better survival rates for children with liver failure
Liver transplantation is currently the only cure for pediatric acute liver failure (PALF), a rapidly progressing and life-threatening condition that can affect previously healthy children. Some children do not get a transplant ...
17 hours ago
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Plant compound used in traditional medicine may help fight tuberculosis
A compound found in African wormwood—a plant used medicinally for thousands of years to treat many types of illness—could be effective against tuberculosis, according to a new study published in the Journal of Ethnopharmacology.
17 hours ago
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Cutting corners results in rare genetic diseases being undiagnosed, say scientists
Inaccurate naming of genetic diseases is resulting in some rare genetic diseases needlessly being undiagnosed, University of Manchester scientists warn. A Nature Genetics communication paper, published today adds to existing ...
18 hours ago
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Long COVID: Study finds lithium aspartate at low doses is ineffective, but higher doses may be promising
A small University at Buffalo clinical trial has found that at low doses, lithium aspartate is ineffective in treating the fatigue and brain fog that is often a persistent feature of long COVID; however, a supplemental dose-finding ...
22 hours ago
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FDA approves Dupixent for chronic obstructive pulmonary disease
The U.S. Food and Drug Administration has approved Regeneron's Dupixent (dupilumab) as an add-on maintenance treatment for adults with inadequately controlled chronic obstructive pulmonary disease (COPD) and an eosinophilic ...
23 hours ago
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Toll in Rwanda Marburg outbreak rises to 11
Five more people in Rwanda have died of the deadly Ebola-like Marburg disease, bringing the number of fatalities to 11, the health ministry said late Tuesday.
Oct 2, 2024
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Mpox vaccination drive delayed in DR Congo
The mpox vaccination campaign in Democratic Republic of Congo has been pushed back, health authorities told AFP on Tuesday, with the exact start date unclear.
Oct 2, 2024
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Guideline on handling endobronchial ultrasound transbronchial needle samples released
The American College of Chest Physicians (CHEST) recently released a new clinical guideline on endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) specimen processing and handling. Published in the ...
Oct 2, 2024
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New mouse models offer valuable window into COVID-19 infection
Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19.
Oct 1, 2024
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Bioinformatics techniques uncover hidden prevalence of repeat expansion disorders
Research led by scientists at Queen Mary University of London is signaling a new era for genetic sequencing and testing. In the largest study of its kind to date, published today in Nature Medicine, an international group ...
Oct 1, 2024
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Promising tuberculosis therapy safe for patients with HIV, finds study
A therapy showing promise to help control tuberculosis (TB) does not interfere with combined antiretroviral therapy (cART), according to research by Texas Biomedical Research Institute (Texas Biomed).
Oct 1, 2024
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Weight-adjusted waist index positively tied to overactive bladder
The weight-adjusted waist index (WWI) may be able to predict future incidence of overactive bladder (OAB) in adults, according to a study published online Sept. 3 in Frontiers in Nutrition.
Oct 1, 2024
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Vitamin deficiencies common in children with nocturnal enuresis
Children with primary nocturnal enuresis may have vitamin D insufficiency and deficiency as well as vitamin B12 deficiency, according to a study published online June 10 in Annals of Medicine.
Oct 1, 2024
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Mosquito-borne virus spread at 'unprecedented' levels in LA County: Climate change may make things worse
Climate change is exacerbating the risk of potentially dangerous mosquito-borne diseases in California—threatening to turn more of those annoying-but-harmless bites into severe illnesses, experts say.
Oct 1, 2024
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FDA approves Miplyffa for treatment of Niemann-Pick disease, type C
The U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).
Oct 1, 2024
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Connecticut has first human case of rare tick-borne disease: First in northeast
The first human case of a rare tick-borne illness has been reported in Connecticut.
Oct 1, 2024
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Researchers discover mechanism driving immune perturbations after severe infections
Researchers at Baylor College of Medicine and collaborating institutions have discovered a mechanism that drives the long-term decline in immune response that is observed after tuberculosis (TB) has been successfully treated. ...
Sep 30, 2024
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COVID-induced immune memory could protect against severe cases of flu, mouse study suggests
More than 200 viruses can infect and cause disease in humans; most of us will be infected by several over the course of a lifetime. Does an encounter with one virus influence how your immune system responds to a different ...
Sep 30, 2024
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Creating a more accurate model of inflammatory bowel disease
A research team led by Junior Associate Professor Kazuo Takayama, from the Department of Cell Growth and Differentiation, recently constructed a new model of inflammatory bowel disease using iPS cells that enables more accurate ...
Sep 30, 2024
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