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Endocrinology & Metabolism news

Health

Major women's health study supports hormone replacement therapy in early menopause

Hormone replacement therapy can safely ease middle-aged women's symptoms during early menopause, data from a major women's health study show.

Neuroscience

Researchers find unexpected link between essential fats and insulin aggregation

Scientists within Texas A&M AgriLife Research have discovered a surprising connection between certain fatty acids and insulin when mixed in solution. Their study, published in ACS Chemical Neuroscience, showed the presence ...

Oncology & Cancer

How cancer cells harness energy to drive disease progression

Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming. This discovery potentially opens up new avenues for cancer treatments that ...

Cardiology

Dietary changes may help treat pulmonary hypertension

Blood vessels in the lungs aren't like the others in the body. This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart ...

Overweight & Obesity

BRD7 research points to alternative insulin signaling pathway

Bromodomain-containing protein 7 (BRD7) was initially identified as a tumor suppressor, but further research has shown it has a broader role in other cellular processes, including the remodeling of chromosomes and cell cycle ...

Overweight & Obesity

New regulator of eating behavior identified

The rapidly escalating prevalence of overweight and obesity poses a significant medical challenge worldwide. In addition to people's changing lifestyles, genetic factors also play a key role in the development of obesity.

Overweight & Obesity

New drug candidate reverses obesity in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' mitochondria. A study published in Nature Metabolism shows that a specific class of drugs that block ...

Biomedical technology

Researchers use the eye as a window to study liver health

Researchers at Karolinska Institutet have developed a method to study liver function and disease without requiring invasive procedures. After transplanting liver cells into the eye of mice, the cornea can be used as a window ...

Medical research

How transcription factors influence insulin-producing beta cells

A recent study from the laboratory of Joseph Bass, MD, Ph.D., the Charles F. Kettering Professor of Medicine and chief of Endocrinology in the Department of Medicine, has revealed how transcription factors within individual ...

Neuroscience

Polycystic ovary syndrome tied to memory, thinking problems

People with polycystic ovary syndrome may be more likely to have memory and thinking problems in middle age, according to new research published in the January 31, 2024, online issue of Neurology. The study does not prove ...

Alzheimer's disease & dementia

Re-energizing mitochondria to treat Alzheimer's disease

Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells. In Alzheimer's disease, the ability to make energy is compromised, and the connections ...

Neuroscience

Decoding how the brain manages the appetite for salt and water

Staying hydrated and consuming appropriate amounts of salt is essential for the survival of terrestrial animals, including humans. The human brain has several regions constituting neural circuits that regulate thirst and ...

Sports medicine & Kinesiology

Too many athletes develop reproductive problems, says researcher

Many athletes compete at the peril of their reproductive health. "This applies to both men and women. Competitive training can affect sex hormones and the ability to have children," says Professor Anthony Hackney.