Obesity increases the body's need for insulin, forcing cells in the pancreas known as beta cells to ramp up insulin production to maintain blood sugar levels. Scientists have thought that this excessive insulin secretion ...
Mar 18, 2026
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Following a rapid increase in popularity of GLP-1 drugs for diabetes and weight loss, such as semaglutide and tirzepatide, approximately one in eight U.S. adults now take these medications, which also provide cardiovascular ...
Mar 18, 2026
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Type 2 diabetes (T2D) and obesity are metabolic conditions with many causes, including overlapping and distinct genetic features. A polygenic risk score (PRS) can capture multiple genetic risk factors to provide an estimate ...
Mar 16, 2026
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The kick-off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a hormone that activates the hypophysis, at the base of the skull, which then releases other hormones ...
Mar 12, 2026
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Northwestern Medicine scientists led by Joseph Bass, MD, Ph.D., the Charles F. Kettering Professor of Endocrinology and Metabolism and director of the Center for Diabetes and Metabolism, have discovered how disruptions in ...
Mar 9, 2026
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GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve cardiovascular health. ...
Mar 6, 2026
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A recent research study found that a combination of the GLP-1 receptor agonist semaglutide and bimagrumab, an antibody that blocks activin signaling pathways, results in greater weight loss while also preserving lean mass, ...
Mar 5, 2026
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A year after stopping taking weight-loss drugs such as Ozempic and Wegovy, people regain—on average—60% of their lost weight. But beyond this, their regained weight plateaus, with individuals managing to keep off 25% of the ...
Mar 4, 2026
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Florida State University researchers have demonstrated that significantly increasing dietary folic acid in mice can prevent peripheral neuropathy, a condition commonly associated with diabetes and other health issues. The ...
Mar 4, 2026
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Scientists at City of Hope and the Broad Institute and Keio University have discovered how specific gut bacteria work together with the diet to flip a metabolic switch—transforming energy-storing white fat into calorie-burning ...
Mar 4, 2026
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